Exploring the inhibitory effect and mechanism of isorhamnetin therapy on oral squamous cell carcinoma based on network pharmacology and molecular docking

Exploring the inhibitory effect and mechanism of isorhamnetin therapy on oral squamous cell carcinoma based on network pharmacology and molecular docking

Objective To explore the mechanism of isorhamnetin (Iso) in the treatment of oral squamous cell carcinoma (OSCC) using network pharmacology and molecular docking methods and to verify it <i>in vitro</i>. Methods The key targets were obtained by constructing the PPI protein interaction ne...

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Bibliographic Details
Main Author: YU Fangfang, ZHOU Jingjing, YANG Jie, QU Huijuan, HUI Guangyan
Format: Article
Language:zho
Published: Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases 2025-01-01
Series:口腔疾病防治
Subjects:
isorhamnetin|oral squamous cell carcinoma|pi3k/akt signaling pathway|src tyrosine kinase|estrogen receptor-1|network pharmacology|molecular docking|experimental verification <i>in vitro</i>
Online Access:https://www.kqjbfz.com/fileup/2096-1456/PDF/2096-1456（2025）01--10.pdf
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