Uptakes of boronophenylalanine in the in vitro and in situ glioblastoma and the potential efficacy of boron neutron capture therapy

Uptakes of boronophenylalanine in the in vitro and in situ glioblastoma and the potential efficacy of boron neutron capture therapy

Human glioblastoma (GBM) is the most malignant brain tumor. Boron neutron capture therapy (BNCT) is proved to be a new technology for the effective treatment of GBM. We previously reported that boronophenylalanine (BPA), the boron drug used in BNCT prefers to the tumor of a mouse subcutaneous tumor...

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Bibliographic Details
Main Authors: Shining Zhang, Yujie Wei, Wenjiao Gu, Shuangyi Li, Ting Liu, Limei Shuai, Yu Tang, Ying Jiang, Xiaochun Zhou, Yucai Wei, Guan Wang, Long Gu, Yumin Li, Futian Tang, Daiying Zuo
Format: Article
Language:English
Published: Elsevier 2025-12-01
Series:IBRO Neuroscience Reports
Subjects:
Boron neutron capture therapy
Boronophenylalanine
Brain tumor cell lines
In situ brain tumor model
Boron distribution
Online Access:http://www.sciencedirect.com/science/article/pii/S2667242125000971
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