A novel anti-epileptogenesis strategy of temporal lobe epilepsy based on nitric oxide donor

A novel anti-epileptogenesis strategy of temporal lobe epilepsy based on nitric oxide donor

Abstract The molecular mechanism underlying the role of hippocampal hilar interneuron degeneration in temporal lobe epilepsy (TLE) remains unclear. Especially, very few studies have focused on the role of neuronal nitric oxide synthase (nNOS, encoded by Nos1) containing hilar interneurons in TLE. In...

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Bibliographic Details
Main Authors: Xian-Hui Zhu, Ya-Ping Zhou, Qiao Zhang, Ming-Yi Zhu, Xiao-Wei Song, Jun Li, Jiang Chen, Yun Shi, Kang-Jian Sun, Yong-Jie Zhang, Jing Zhang, Tian Xia, Bao-Sheng Huang, Fan Meng, Qi-Gang Zhou
Format: Article
Language:English
Published: Springer Nature 2024-12-01
Series:EMBO Molecular Medicine
Subjects:
Epileptogenesis
Neuronal Nitric Oxide Synthase
Hilar Interneurons
Dentate Granule Cells
Pilocarpine
Online Access:https://doi.org/10.1038/s44321-024-00168-1
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https://doi.org/10.1038/s44321-024-00168-1

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