Decoding post-transcriptional gene expression controls in trypanosomatids using machine learning [version 2; peer review: 2 approved]

Background We recently described a pervasive cis-regulatory role for sequences in Trypanosoma brucei mRNA untranslated regions (UTRs). Specifically, increased translation efficiency (TE) was associated with the dosage and density of A-rich tracts. This finding raised three related questions: (1) Wha...

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Bibliographic Details
Main Authors: David Horn, Michele Tinti
Format: Article
Language:English
Published: Wellcome 2025-07-01
Series:Wellcome Open Research
Subjects:
Online Access:https://wellcomeopenresearch.org/articles/10-173/v2
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