Evaluation of feasibility accuracy and safety after 79 O-ARM based stereotactic brain biopsies
Abstract Frame-based Stereotactic Brain Biopsy (FSBB) is a minimally invasive procedure with a view to increasing the diagnostic yield. The aim of this study was to investigate the accuracy and safety of FSBB with the help of the intraoperative 3D O-ARM system. A preoperative MRI allowed for targeti...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-01-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-86069-w |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832585702002393088 |
|---|---|
| author | Inès Bouscatel Benoit Marlier Claude-Fabien Litré Valéry Batchinsky-Parrou Maxime Rivollier Stanislas Loniewski Jean-Charles Kleiber |
| author_facet | Inès Bouscatel Benoit Marlier Claude-Fabien Litré Valéry Batchinsky-Parrou Maxime Rivollier Stanislas Loniewski Jean-Charles Kleiber |
| author_sort | Inès Bouscatel |
| collection | DOAJ |
| description | Abstract Frame-based Stereotactic Brain Biopsy (FSBB) is a minimally invasive procedure with a view to increasing the diagnostic yield. The aim of this study was to investigate the accuracy and safety of FSBB with the help of the intraoperative 3D O-ARM system. A preoperative MRI allowed for targeting the tissue to be sampled. A Leksell stereotactic frame was bolted to patient’s skull in the operating room, and we proceeded to the intraoperative 3D O-ARM acquisition. A software platform was used to calculate stereotactic coordinates through combining both exams. A second 3D O-ARM acquisition was performed to control the final needle target point. A total of 79 patients were included in our study population, 68 biopsies (86.1%) yielded the diagnosis. Biopsy-related complications occurred in 11 patients (13.9%), of whom 8 were successfully diagnosed. Per and post-procedure complications occurred in 3 (3.8%) and 8 cases (10.1%) respectively. Mean operating time was 102 min. FSBB using the intraoperative 3D O-ARM system is a promising alternative. The rate of non-contributory biopsies is moderate given that this new procedure is conducted in the operating room from beginning to end. Complications were not directly linked to the procedure and does not compromise the diagnosis. |
| format | Article |
| id | doaj-art-4735cf31c1ac46be864bbf99b33aee0f |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-4735cf31c1ac46be864bbf99b33aee0f2025-01-26T12:32:53ZengNature PortfolioScientific Reports2045-23222025-01-0115111510.1038/s41598-025-86069-wEvaluation of feasibility accuracy and safety after 79 O-ARM based stereotactic brain biopsiesInès Bouscatel0Benoit Marlier1Claude-Fabien Litré2Valéry Batchinsky-Parrou3Maxime Rivollier4Stanislas Loniewski5Jean-Charles Kleiber6Department of Neurosurgery, Reims University HospitalDepartment of Neurosurgery, Reims University HospitalDepartment of Neurosurgery, Reims University HospitalDepartment of Neurosurgery, Reims University HospitalDepartment of Neurosurgery, Reims University HospitalDepartment of Neurosurgery, Reims University HospitalDepartment of Neurosurgery, Reims University HospitalAbstract Frame-based Stereotactic Brain Biopsy (FSBB) is a minimally invasive procedure with a view to increasing the diagnostic yield. The aim of this study was to investigate the accuracy and safety of FSBB with the help of the intraoperative 3D O-ARM system. A preoperative MRI allowed for targeting the tissue to be sampled. A Leksell stereotactic frame was bolted to patient’s skull in the operating room, and we proceeded to the intraoperative 3D O-ARM acquisition. A software platform was used to calculate stereotactic coordinates through combining both exams. A second 3D O-ARM acquisition was performed to control the final needle target point. A total of 79 patients were included in our study population, 68 biopsies (86.1%) yielded the diagnosis. Biopsy-related complications occurred in 11 patients (13.9%), of whom 8 were successfully diagnosed. Per and post-procedure complications occurred in 3 (3.8%) and 8 cases (10.1%) respectively. Mean operating time was 102 min. FSBB using the intraoperative 3D O-ARM system is a promising alternative. The rate of non-contributory biopsies is moderate given that this new procedure is conducted in the operating room from beginning to end. Complications were not directly linked to the procedure and does not compromise the diagnosis.https://doi.org/10.1038/s41598-025-86069-wBrain neoplasmsBrain biopsyStereotactic techniquesIntraoperative Imaging |
| spellingShingle | Inès Bouscatel Benoit Marlier Claude-Fabien Litré Valéry Batchinsky-Parrou Maxime Rivollier Stanislas Loniewski Jean-Charles Kleiber Evaluation of feasibility accuracy and safety after 79 O-ARM based stereotactic brain biopsies Scientific Reports Brain neoplasms Brain biopsy Stereotactic techniques Intraoperative Imaging |
| title | Evaluation of feasibility accuracy and safety after 79 O-ARM based stereotactic brain biopsies |
| title_full | Evaluation of feasibility accuracy and safety after 79 O-ARM based stereotactic brain biopsies |
| title_fullStr | Evaluation of feasibility accuracy and safety after 79 O-ARM based stereotactic brain biopsies |
| title_full_unstemmed | Evaluation of feasibility accuracy and safety after 79 O-ARM based stereotactic brain biopsies |
| title_short | Evaluation of feasibility accuracy and safety after 79 O-ARM based stereotactic brain biopsies |
| title_sort | evaluation of feasibility accuracy and safety after 79 o arm based stereotactic brain biopsies |
| topic | Brain neoplasms Brain biopsy Stereotactic techniques Intraoperative Imaging |
| url | https://doi.org/10.1038/s41598-025-86069-w |
| work_keys_str_mv | AT inesbouscatel evaluationoffeasibilityaccuracyandsafetyafter79oarmbasedstereotacticbrainbiopsies AT benoitmarlier evaluationoffeasibilityaccuracyandsafetyafter79oarmbasedstereotacticbrainbiopsies AT claudefabienlitre evaluationoffeasibilityaccuracyandsafetyafter79oarmbasedstereotacticbrainbiopsies AT valerybatchinskyparrou evaluationoffeasibilityaccuracyandsafetyafter79oarmbasedstereotacticbrainbiopsies AT maximerivollier evaluationoffeasibilityaccuracyandsafetyafter79oarmbasedstereotacticbrainbiopsies AT stanislasloniewski evaluationoffeasibilityaccuracyandsafetyafter79oarmbasedstereotacticbrainbiopsies AT jeancharleskleiber evaluationoffeasibilityaccuracyandsafetyafter79oarmbasedstereotacticbrainbiopsies |