Association of preoperative to postoperative change in cerebrospinal fluid fibrinogen with postoperative delirium

Association of preoperative to postoperative change in cerebrospinal fluid fibrinogen with postoperative delirium

Background: We aimed to assess perioperative changes in fibrinogen in the cerebrospinal fluid (CSF), their association with markers of blood–brain barrier breakdown and neuroinflammation, and their association with postoperative delirium severity. Methods: We conducted a secondary analysis of the In...

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Bibliographic Details
Main Authors: Thomas Payne, Jennifer Taylor, David Kunkel, Katherine Konieczka, Frankie Ingram, Kaj Blennow, Henrik Zetterberg, Robert A. Pearce, Anke Meyer-Franke, Niccolò Terrando, Katerina Akassoglou, Robert D. Sanders, Richard C. Lennertz
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:BJA Open
Subjects:
anaesthesia
cerebrospinal fluid
delirium
fibrinogen
neurocognitive disorders
surgery
Online Access:http://www.sciencedirect.com/science/article/pii/S2772609624000935
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