Antibody Response in Seropositive Multiple Sclerosis Patients Vaccinated with Attenuated Live Varicella Zoster Virus
OBJECTIVE: To determine the safety and effectiveness of live attenuated varicella zoster virus (VZV) vaccine (OKA/Merck) on 50 patients with chronic progressive multiple sclerosis (MS), based on the hypothesis that VZV might be the antigen or antigen mimic of MS plus the fact that repeated high anti...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
1996-01-01
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| Series: | Canadian Journal of Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/1996/417061 |
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| _version_ | 1832559823586066432 |
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| author | RT Ross MR Dawood Mary Cheang Lindsay E Nicolle |
| author_facet | RT Ross MR Dawood Mary Cheang Lindsay E Nicolle |
| author_sort | RT Ross |
| collection | DOAJ |
| description | OBJECTIVE: To determine the safety and effectiveness of live attenuated varicella zoster virus (VZV) vaccine (OKA/Merck) on 50 patients with chronic progressive multiple sclerosis (MS), based on the hypothesis that VZV might be the antigen or antigen mimic of MS plus the fact that repeated high antigen doses have produced ‘antigen paralysis’ in experimental allergic encephalomyelitis mice. |
| format | Article |
| id | doaj-art-46660abdabdc441eaf10b1ed6f087c99 |
| institution | Kabale University |
| issn | 1180-2332 |
| language | English |
| publishDate | 1996-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases |
| spelling | doaj-art-46660abdabdc441eaf10b1ed6f087c992025-02-03T01:29:09ZengWileyCanadian Journal of Infectious Diseases1180-23321996-01-017530330610.1155/1996/417061Antibody Response in Seropositive Multiple Sclerosis Patients Vaccinated with Attenuated Live Varicella Zoster VirusRT Ross0MR Dawood1Mary Cheang2Lindsay E Nicolle3Section of Neurology, University of Manitoba, Winnipeg, Manitoba, CanadaInfectious Diseases and Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, CanadaBiostatistical Consulting Unit Community Health Sciences, University of Manitoba, Winnipeg, Manitoba, CanadaInfectious Diseases and Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, CanadaOBJECTIVE: To determine the safety and effectiveness of live attenuated varicella zoster virus (VZV) vaccine (OKA/Merck) on 50 patients with chronic progressive multiple sclerosis (MS), based on the hypothesis that VZV might be the antigen or antigen mimic of MS plus the fact that repeated high antigen doses have produced ‘antigen paralysis’ in experimental allergic encephalomyelitis mice.http://dx.doi.org/10.1155/1996/417061 |
| spellingShingle | RT Ross MR Dawood Mary Cheang Lindsay E Nicolle Antibody Response in Seropositive Multiple Sclerosis Patients Vaccinated with Attenuated Live Varicella Zoster Virus Canadian Journal of Infectious Diseases |
| title | Antibody Response in Seropositive Multiple Sclerosis Patients Vaccinated with Attenuated Live Varicella Zoster Virus |
| title_full | Antibody Response in Seropositive Multiple Sclerosis Patients Vaccinated with Attenuated Live Varicella Zoster Virus |
| title_fullStr | Antibody Response in Seropositive Multiple Sclerosis Patients Vaccinated with Attenuated Live Varicella Zoster Virus |
| title_full_unstemmed | Antibody Response in Seropositive Multiple Sclerosis Patients Vaccinated with Attenuated Live Varicella Zoster Virus |
| title_short | Antibody Response in Seropositive Multiple Sclerosis Patients Vaccinated with Attenuated Live Varicella Zoster Virus |
| title_sort | antibody response in seropositive multiple sclerosis patients vaccinated with attenuated live varicella zoster virus |
| url | http://dx.doi.org/10.1155/1996/417061 |
| work_keys_str_mv | AT rtross antibodyresponseinseropositivemultiplesclerosispatientsvaccinatedwithattenuatedlivevaricellazostervirus AT mrdawood antibodyresponseinseropositivemultiplesclerosispatientsvaccinatedwithattenuatedlivevaricellazostervirus AT marycheang antibodyresponseinseropositivemultiplesclerosispatientsvaccinatedwithattenuatedlivevaricellazostervirus AT lindsayenicolle antibodyresponseinseropositivemultiplesclerosispatientsvaccinatedwithattenuatedlivevaricellazostervirus |