Cetobacterium somerae-derived argininosuccinic acid promotes intestinal and liver ureagenesis to alleviate ammonia intoxication

Abstract Background Ammonia generated from amino acid metabolism is a cytotoxin that can adversely affect cell function and overall health and potentially lead to cellular toxicity and death due to its accumulation. Previous studies have shown that acute ammonia intoxication (AI) can increase the in...

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Bibliographic Details
Main Authors: Shidong Wang, Xue Li, Muzi Zhang, Ming Li
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Microbiome
Subjects:
Online Access:https://doi.org/10.1186/s40168-025-02152-4
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