Adropin as an indicator of T2DM and its complications
Type 2 diabetes mellitus (T2DM) is one of metabolic diseases with the major inducer of obesity. Due to the change in lifestyle and dietary structure, more and more people are being suffered from T2DM. Therefore, the prevention and treatment of T2DM and its complications has become an urgent problem...
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Tsinghua University Press
2022-11-01
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| Series: | Food Science and Human Wellness |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213453022000854 |
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| author | Hu Zhang Ning Chen |
| author_facet | Hu Zhang Ning Chen |
| author_sort | Hu Zhang |
| collection | DOAJ |
| description | Type 2 diabetes mellitus (T2DM) is one of metabolic diseases with the major inducer of obesity. Due to the change in lifestyle and dietary structure, more and more people are being suffered from T2DM. Therefore, the prevention and treatment of T2DM and its complications has become an urgent problem to be solved. As a secreted peptide, adropin is identified as a useful regulator associated with insulin sensitivity and energy homeostasis. It has the potential for regulating metabolic diseases including obesity and T2DM. It should be noted that the secretion of adropin can be induced by diets, aerobic exercise and other interventions. In this article, the underlying mechanisms of adropin for regulating obesity, T2DM and its complications including diabetic nephropathy, diabetic retinopathy, diabetic encephalopathy, diabetic vascular disease and diabetic cardiovascular disease were summarized. Meanwhile, the strategies for promoting the secretion of adropin were also discussed, which will provide a target for the prevention and targeted treatment, or a candidate of novel and effective functional food or drug for metabolic diseases in the future. |
| format | Article |
| id | doaj-art-4644b7f5e1a74f35aea97b132ef8f735 |
| institution | Kabale University |
| issn | 2213-4530 |
| language | English |
| publishDate | 2022-11-01 |
| publisher | Tsinghua University Press |
| record_format | Article |
| series | Food Science and Human Wellness |
| spelling | doaj-art-4644b7f5e1a74f35aea97b132ef8f7352025-02-02T23:24:56ZengTsinghua University PressFood Science and Human Wellness2213-45302022-11-0111614551463Adropin as an indicator of T2DM and its complicationsHu Zhang0Ning Chen1Graduate School, Wuhan Sports University, Wuhan 430079, ChinaTianjiu Research and Development Center for Exercise Nutrition and Foods, Hubei Key Laboratory of Exercise Training and Monitoring, College of Health Science, Wuhan Sports University, Wuhan 430079, China; Corresponding author at: College of Health Science, Wuhan Sports University, Wuhan 430079, China.Type 2 diabetes mellitus (T2DM) is one of metabolic diseases with the major inducer of obesity. Due to the change in lifestyle and dietary structure, more and more people are being suffered from T2DM. Therefore, the prevention and treatment of T2DM and its complications has become an urgent problem to be solved. As a secreted peptide, adropin is identified as a useful regulator associated with insulin sensitivity and energy homeostasis. It has the potential for regulating metabolic diseases including obesity and T2DM. It should be noted that the secretion of adropin can be induced by diets, aerobic exercise and other interventions. In this article, the underlying mechanisms of adropin for regulating obesity, T2DM and its complications including diabetic nephropathy, diabetic retinopathy, diabetic encephalopathy, diabetic vascular disease and diabetic cardiovascular disease were summarized. Meanwhile, the strategies for promoting the secretion of adropin were also discussed, which will provide a target for the prevention and targeted treatment, or a candidate of novel and effective functional food or drug for metabolic diseases in the future.http://www.sciencedirect.com/science/article/pii/S2213453022000854AdropinMetabolic diseaseObesityT2DMDiabetic complications |
| spellingShingle | Hu Zhang Ning Chen Adropin as an indicator of T2DM and its complications Food Science and Human Wellness Adropin Metabolic disease Obesity T2DM Diabetic complications |
| title | Adropin as an indicator of T2DM and its complications |
| title_full | Adropin as an indicator of T2DM and its complications |
| title_fullStr | Adropin as an indicator of T2DM and its complications |
| title_full_unstemmed | Adropin as an indicator of T2DM and its complications |
| title_short | Adropin as an indicator of T2DM and its complications |
| title_sort | adropin as an indicator of t2dm and its complications |
| topic | Adropin Metabolic disease Obesity T2DM Diabetic complications |
| url | http://www.sciencedirect.com/science/article/pii/S2213453022000854 |
| work_keys_str_mv | AT huzhang adropinasanindicatoroft2dmanditscomplications AT ningchen adropinasanindicatoroft2dmanditscomplications |