Dengue Outbreak in a Hilly State of Arunachal Pradesh in Northeast India

Dengue has been reported from plains as well as hilly regions of India including some parts of Northeast India. In July-August 2012, outbreak of fever with unknown origin (FUO) indicative of Dengue was reported in Pasighat, East Siang district of Arunachal Pradesh (AP) state. Serum samples (n = 164)...

Full description

Saved in:
Bibliographic Details
Main Authors: Siraj A. Khan, Prafulla Dutta, Rashmee Topno, Monika Soni, Jagadish Mahanta
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2014/584093
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832560940155928576
author Siraj A. Khan
Prafulla Dutta
Rashmee Topno
Monika Soni
Jagadish Mahanta
author_facet Siraj A. Khan
Prafulla Dutta
Rashmee Topno
Monika Soni
Jagadish Mahanta
author_sort Siraj A. Khan
collection DOAJ
description Dengue has been reported from plains as well as hilly regions of India including some parts of Northeast India. In July-August 2012, outbreak of fever with unknown origin (FUO) indicative of Dengue was reported in Pasighat, East Siang district of Arunachal Pradesh (AP) state. Serum samples (n = 164) collected from patients from Health Training and Research Centre General Hospital, Pasighat, were tested for NS1 antigen and IgM antibodies. NS1-positive samples were analyzed by RT-PCR assay and entomological surveys were carried out. The majority of suspected cases reported NS1 antigen positivity. Females and young adults were mostly affected. The majority of the amplified NS1-positive samples showed Dengue serotype 3 infection. Aedes (Stegomyia) albopictus, known as semiurban breeding mosquitoes, was the only potential vector species identified from the affected areas of Pasighat which single handedly contributed to the outbreak. Thus, the present work identifies Dengue as an emerging arboviral infection in hilly state of AP along with a looming risk of its spread to neighbouring areas.
format Article
id doaj-art-45dd8d075a9e47fb86b35e1c15550fe2
institution Kabale University
issn 2356-6140
1537-744X
language English
publishDate 2014-01-01
publisher Wiley
record_format Article
series The Scientific World Journal
spelling doaj-art-45dd8d075a9e47fb86b35e1c15550fe22025-02-03T01:26:16ZengWileyThe Scientific World Journal2356-61401537-744X2014-01-01201410.1155/2014/584093584093Dengue Outbreak in a Hilly State of Arunachal Pradesh in Northeast IndiaSiraj A. Khan0Prafulla Dutta1Rashmee Topno2Monika Soni3Jagadish Mahanta4Entomology and Filariasis Division, Regional Medical Research Centre, (ICMR), NE Region, P.O. Box 105, Dibrugarh, Assam, IndiaEntomology and Filariasis Division, Regional Medical Research Centre, (ICMR), NE Region, P.O. Box 105, Dibrugarh, Assam, IndiaEntomology and Filariasis Division, Regional Medical Research Centre, (ICMR), NE Region, P.O. Box 105, Dibrugarh, Assam, IndiaEntomology and Filariasis Division, Regional Medical Research Centre, (ICMR), NE Region, P.O. Box 105, Dibrugarh, Assam, IndiaEntomology and Filariasis Division, Regional Medical Research Centre, (ICMR), NE Region, P.O. Box 105, Dibrugarh, Assam, IndiaDengue has been reported from plains as well as hilly regions of India including some parts of Northeast India. In July-August 2012, outbreak of fever with unknown origin (FUO) indicative of Dengue was reported in Pasighat, East Siang district of Arunachal Pradesh (AP) state. Serum samples (n = 164) collected from patients from Health Training and Research Centre General Hospital, Pasighat, were tested for NS1 antigen and IgM antibodies. NS1-positive samples were analyzed by RT-PCR assay and entomological surveys were carried out. The majority of suspected cases reported NS1 antigen positivity. Females and young adults were mostly affected. The majority of the amplified NS1-positive samples showed Dengue serotype 3 infection. Aedes (Stegomyia) albopictus, known as semiurban breeding mosquitoes, was the only potential vector species identified from the affected areas of Pasighat which single handedly contributed to the outbreak. Thus, the present work identifies Dengue as an emerging arboviral infection in hilly state of AP along with a looming risk of its spread to neighbouring areas.http://dx.doi.org/10.1155/2014/584093
spellingShingle Siraj A. Khan
Prafulla Dutta
Rashmee Topno
Monika Soni
Jagadish Mahanta
Dengue Outbreak in a Hilly State of Arunachal Pradesh in Northeast India
The Scientific World Journal
title Dengue Outbreak in a Hilly State of Arunachal Pradesh in Northeast India
title_full Dengue Outbreak in a Hilly State of Arunachal Pradesh in Northeast India
title_fullStr Dengue Outbreak in a Hilly State of Arunachal Pradesh in Northeast India
title_full_unstemmed Dengue Outbreak in a Hilly State of Arunachal Pradesh in Northeast India
title_short Dengue Outbreak in a Hilly State of Arunachal Pradesh in Northeast India
title_sort dengue outbreak in a hilly state of arunachal pradesh in northeast india
url http://dx.doi.org/10.1155/2014/584093
work_keys_str_mv AT sirajakhan dengueoutbreakinahillystateofarunachalpradeshinnortheastindia
AT prafulladutta dengueoutbreakinahillystateofarunachalpradeshinnortheastindia
AT rashmeetopno dengueoutbreakinahillystateofarunachalpradeshinnortheastindia
AT monikasoni dengueoutbreakinahillystateofarunachalpradeshinnortheastindia
AT jagadishmahanta dengueoutbreakinahillystateofarunachalpradeshinnortheastindia