Steady-state metabolite concentrations reflect a balance between maximizing enzyme efficiency and minimizing total metabolite load.
Steady-state metabolite concentrations in a microorganism typically span several orders of magnitude. The underlying principles governing these concentrations remain poorly understood. Here, we hypothesize that observed variation can be explained in terms of a compromise between factors that favor m...
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| Main Authors: | Naama Tepper, Elad Noor, Daniel Amador-Noguez, Hulda S Haraldsdóttir, Ron Milo, Josh Rabinowitz, Wolfram Liebermeister, Tomer Shlomi |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2013-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0075370&type=printable |
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