Compositional data analysis enables statistical rigor in comparative glycomics

Abstract Comparative glycomics data are compositional data, where measured glycans are parts of a whole, indicated by relative abundances. Applying traditional statistical analyses to these data often results in misleading conclusions, such as spurious “decreases” of glycans when other structures in...

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Bibliographic Details
Main Authors: Alexander R. Bennett, Jon Lundstrøm, Sayantani Chatterjee, Morten Thaysen-Andersen, Daniel Bojar
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56249-3
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