Counteracting Alzheimer's disease via normalizing neurovascular unit with a self-regulated multi-functional nano-modulator

Counteracting Alzheimer's disease via normalizing neurovascular unit with a self-regulated multi-functional nano-modulator

The neurovascular unit (NVU) is highly responsible for cerebral homeostasis and its dysfunction emerges as a critical contributor to Alzheimer's disease (AD) pathology. Hence, rescuing NVU dysfunction might be a viable approach to AD treatments. Here, we fabricated a self-regulated muti-functio...

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Bibliographic Details
Main Authors: Xue Xia, Ya Wei, Qianqian Huang, Yang Zhou, Xiaorong Wang, Yulong Shi, Xiaotong Yang, Wenqin Yang, Yiwei Zhang, Ting Lei, Yuan Huang, Hanmei Li, Meng Qin, Huile Gao
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Alzheimer's disease
Targeted delivery
Pathological blood–brain barrier
Neurovascular unit
Receptor for advanced glycation end products
Gene delivery
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383524001941
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