In Vitro Model of Vascular Remodeling Under Microfluidic Perfusion

In Vitro Model of Vascular Remodeling Under Microfluidic Perfusion

We developed a portable microfluidic system that combines spontaneous lumen formation from human umbilical endothelial cells (HUVECs) in fibrin–collagen hydrogels with active perfusion controlled by a braille actuator. Adaptive interstitial flow and feedthrough perfusion switching enabled the succes...

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Bibliographic Details
Main Authors: Kotaro Nishikata, Kimisato Doi, Nobuyoshi Kaneoya, Masataka Nakamura, Nobuyuki Futai
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Micromachines
Subjects:
remodeling
spontaneous
vascular network
microfluidic
centrality
Online Access:https://www.mdpi.com/2072-666X/16/1/14
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