Modulation of glymphatic system by visual circuit activation alleviates memory impairment and apathy in a mouse model of Alzheimer’s disease

Modulation of glymphatic system by visual circuit activation alleviates memory impairment and apathy in a mouse model of Alzheimer’s disease

Abstract Alzheimer’s disease is characterized by progressive amyloid deposition and cognitive decline, yet the pathological mechanisms and treatments remain elusive. Here we report the therapeutic potential of low-intensity 40 hertz blue light exposure in a 5xFAD mouse model of Alzheimer’s disease....

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Main Authors: Wen Wu, Yubai Zhao, Xin Cheng, Xiaoru Xie, Yixiu Zeng, Quan Tao, Yishuai Yang, Chuan Xiao, Zhan Zhang, Jiahui Pang, Jian Jin, Hongbo He, Yangyang Lin, Boxing Li, Junxian Ma, Xiaojing Ye, Wei-Jye Lin
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55678-w
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https://doi.org/10.1038/s41467-024-55678-w

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