Combination of APACHE Scoring Systems with Adductor Pollicis Muscle Thickness for the Prediction of Mortality in Patients Who Spend More Than One Day in the Intensive Care Unit

Background. The objective of the present study was to compare the ability of Acute Physiology and Chronic Health Evaluation (APACHE) scoring systems with the combination of an anthropometric variable score “adductor pollicis muscle (APM) thickness” to the APACHE systems in predicting mortality in th...

Full description

Saved in:
Bibliographic Details
Main Authors: Elahe Nematifard, Seyed Hossein Ardehali, Shaahin Shahbazi, Hassan Eini-Zinab, Zahra Vahdat Shariatpanahi
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Critical Care Research and Practice
Online Access:http://dx.doi.org/10.1155/2018/5490346
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832567167236702208
author Elahe Nematifard
Seyed Hossein Ardehali
Shaahin Shahbazi
Hassan Eini-Zinab
Zahra Vahdat Shariatpanahi
author_facet Elahe Nematifard
Seyed Hossein Ardehali
Shaahin Shahbazi
Hassan Eini-Zinab
Zahra Vahdat Shariatpanahi
author_sort Elahe Nematifard
collection DOAJ
description Background. The objective of the present study was to compare the ability of Acute Physiology and Chronic Health Evaluation (APACHE) scoring systems with the combination of an anthropometric variable score “adductor pollicis muscle (APM) thickness” to the APACHE systems in predicting mortality in the intensive care unit. Methods. A prospective observational study was conducted with the APM thickness in the dominant hand, and APACHE II and III scores were measured for each patient upon admission. Given scores for the APM thickness were added to APACHE score systems to make two composite scores of APACHE II-APM and APACHE III-APM. The accuracy of the two composite models and APACHE II and III systems in predicting mortality of patients was compared using the area under the ROC curve. Results. Three hundred and four patients with the mean age of 54.75 ± 18.28 years were studied, of which 96 (31.57%) patients died. Median (interquartile range) of APACHE II and III scores was 15 (12–20) and 47 (33–66), respectively. Median (interquartile range) of APM thickness was 15 (12–17) mm, respectively. The area under the ROC curves for the prediction of mortality was 0.771 (95% CI: 0.715–0.827), 0.802 (95% CI: 0.751–0.854), 0.851 (95% CI: 0.807–0.896), and 0.865 (95% CI: 0.822–0.908) for APACHE II, APACHE III, APACHE II-APM, and APACHE III-APM, respectively. Conclusion. Although improvements in the area under ROC curves were not statistically significant when the APM thickness added to the APACHE systems, but the numerical value added to AUCs are considerable.
format Article
id doaj-art-45247734e37e402ab7b02e32c396f19c
institution Kabale University
issn 2090-1305
2090-1313
language English
publishDate 2018-01-01
publisher Wiley
record_format Article
series Critical Care Research and Practice
spelling doaj-art-45247734e37e402ab7b02e32c396f19c2025-02-03T01:02:16ZengWileyCritical Care Research and Practice2090-13052090-13132018-01-01201810.1155/2018/54903465490346Combination of APACHE Scoring Systems with Adductor Pollicis Muscle Thickness for the Prediction of Mortality in Patients Who Spend More Than One Day in the Intensive Care UnitElahe Nematifard0Seyed Hossein Ardehali1Shaahin Shahbazi2Hassan Eini-Zinab3Zahra Vahdat Shariatpanahi4International Branch, Shahid Beheshti University of Medical Sciences, Tehran, IranDepartment of Anesthesiology and Critical Care, Shohada Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IranDepartment of Internal Medicine, Mostafa Khomaini Hospital, Ilam University of Medical Sciences, Ilam, IranDepartment of Community Nutrition, National Nutrition and Food Technology Research Institute, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, IranDepartment of Clinical Nutrition, National Nutrition and Food Technology Research Institute, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, IranBackground. The objective of the present study was to compare the ability of Acute Physiology and Chronic Health Evaluation (APACHE) scoring systems with the combination of an anthropometric variable score “adductor pollicis muscle (APM) thickness” to the APACHE systems in predicting mortality in the intensive care unit. Methods. A prospective observational study was conducted with the APM thickness in the dominant hand, and APACHE II and III scores were measured for each patient upon admission. Given scores for the APM thickness were added to APACHE score systems to make two composite scores of APACHE II-APM and APACHE III-APM. The accuracy of the two composite models and APACHE II and III systems in predicting mortality of patients was compared using the area under the ROC curve. Results. Three hundred and four patients with the mean age of 54.75 ± 18.28 years were studied, of which 96 (31.57%) patients died. Median (interquartile range) of APACHE II and III scores was 15 (12–20) and 47 (33–66), respectively. Median (interquartile range) of APM thickness was 15 (12–17) mm, respectively. The area under the ROC curves for the prediction of mortality was 0.771 (95% CI: 0.715–0.827), 0.802 (95% CI: 0.751–0.854), 0.851 (95% CI: 0.807–0.896), and 0.865 (95% CI: 0.822–0.908) for APACHE II, APACHE III, APACHE II-APM, and APACHE III-APM, respectively. Conclusion. Although improvements in the area under ROC curves were not statistically significant when the APM thickness added to the APACHE systems, but the numerical value added to AUCs are considerable.http://dx.doi.org/10.1155/2018/5490346
spellingShingle Elahe Nematifard
Seyed Hossein Ardehali
Shaahin Shahbazi
Hassan Eini-Zinab
Zahra Vahdat Shariatpanahi
Combination of APACHE Scoring Systems with Adductor Pollicis Muscle Thickness for the Prediction of Mortality in Patients Who Spend More Than One Day in the Intensive Care Unit
Critical Care Research and Practice
title Combination of APACHE Scoring Systems with Adductor Pollicis Muscle Thickness for the Prediction of Mortality in Patients Who Spend More Than One Day in the Intensive Care Unit
title_full Combination of APACHE Scoring Systems with Adductor Pollicis Muscle Thickness for the Prediction of Mortality in Patients Who Spend More Than One Day in the Intensive Care Unit
title_fullStr Combination of APACHE Scoring Systems with Adductor Pollicis Muscle Thickness for the Prediction of Mortality in Patients Who Spend More Than One Day in the Intensive Care Unit
title_full_unstemmed Combination of APACHE Scoring Systems with Adductor Pollicis Muscle Thickness for the Prediction of Mortality in Patients Who Spend More Than One Day in the Intensive Care Unit
title_short Combination of APACHE Scoring Systems with Adductor Pollicis Muscle Thickness for the Prediction of Mortality in Patients Who Spend More Than One Day in the Intensive Care Unit
title_sort combination of apache scoring systems with adductor pollicis muscle thickness for the prediction of mortality in patients who spend more than one day in the intensive care unit
url http://dx.doi.org/10.1155/2018/5490346
work_keys_str_mv AT elahenematifard combinationofapachescoringsystemswithadductorpollicismusclethicknessforthepredictionofmortalityinpatientswhospendmorethanonedayintheintensivecareunit
AT seyedhosseinardehali combinationofapachescoringsystemswithadductorpollicismusclethicknessforthepredictionofmortalityinpatientswhospendmorethanonedayintheintensivecareunit
AT shaahinshahbazi combinationofapachescoringsystemswithadductorpollicismusclethicknessforthepredictionofmortalityinpatientswhospendmorethanonedayintheintensivecareunit
AT hassaneinizinab combinationofapachescoringsystemswithadductorpollicismusclethicknessforthepredictionofmortalityinpatientswhospendmorethanonedayintheintensivecareunit
AT zahravahdatshariatpanahi combinationofapachescoringsystemswithadductorpollicismusclethicknessforthepredictionofmortalityinpatientswhospendmorethanonedayintheintensivecareunit