Should My Patient with Inflammatory Bowel Disease on Immunosuppressive Therapy be Vaccinated against Influenza Virus?
Crohn’s disease and ulcerative colitis are variants of inflammatory bowel disease (IBD) for which immunosuppressive therapy is often required. Immunosuppressed patients are at increased risk for infections, including vaccine-preventable diseases such as influenza. Although several guidelines recomme...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/2010/375878 |
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| _version_ | 1832561010322440192 |
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| author | Neeraj Narula Deborah LR Yamamura John K Marshall |
| author_facet | Neeraj Narula Deborah LR Yamamura John K Marshall |
| author_sort | Neeraj Narula |
| collection | DOAJ |
| description | Crohn’s disease and ulcerative colitis are variants of inflammatory bowel disease (IBD) for which immunosuppressive therapy is often required. Immunosuppressed patients are at increased risk for infections, including vaccine-preventable diseases such as influenza. Although several guidelines recommend routine influenza immunization for such patients, recent literature suggests that this patient population may be inadequately immunized. Current research suggests that inactivated influenza vaccines are effective, well tolerated and can be administered safely in most IBD patients. Studies in other immunosuppressed populations have also demonstrated the safety of inactivated vaccines. The present article reviews the literature regarding the safety and efficacy of influenza vaccination in IBD patients receiving immunosuppressive therapy. |
| format | Article |
| id | doaj-art-44f99cba1d894fa4a7616632102c65c0 |
| institution | Kabale University |
| issn | 0835-7900 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-44f99cba1d894fa4a7616632102c65c02025-02-03T01:26:12ZengWileyCanadian Journal of Gastroenterology0835-79002010-01-0124212112510.1155/2010/375878Should My Patient with Inflammatory Bowel Disease on Immunosuppressive Therapy be Vaccinated against Influenza Virus?Neeraj Narula0Deborah LR Yamamura1John K Marshall2Department of Medicine (Division of Gastroenterology) and Farncombe Family Digestive Health Research Institute, CanadaDepartment of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, CanadaDepartment of Medicine (Division of Gastroenterology) and Farncombe Family Digestive Health Research Institute, CanadaCrohn’s disease and ulcerative colitis are variants of inflammatory bowel disease (IBD) for which immunosuppressive therapy is often required. Immunosuppressed patients are at increased risk for infections, including vaccine-preventable diseases such as influenza. Although several guidelines recommend routine influenza immunization for such patients, recent literature suggests that this patient population may be inadequately immunized. Current research suggests that inactivated influenza vaccines are effective, well tolerated and can be administered safely in most IBD patients. Studies in other immunosuppressed populations have also demonstrated the safety of inactivated vaccines. The present article reviews the literature regarding the safety and efficacy of influenza vaccination in IBD patients receiving immunosuppressive therapy.http://dx.doi.org/10.1155/2010/375878 |
| spellingShingle | Neeraj Narula Deborah LR Yamamura John K Marshall Should My Patient with Inflammatory Bowel Disease on Immunosuppressive Therapy be Vaccinated against Influenza Virus? Canadian Journal of Gastroenterology |
| title | Should My Patient with Inflammatory Bowel Disease on Immunosuppressive Therapy be Vaccinated against Influenza Virus? |
| title_full | Should My Patient with Inflammatory Bowel Disease on Immunosuppressive Therapy be Vaccinated against Influenza Virus? |
| title_fullStr | Should My Patient with Inflammatory Bowel Disease on Immunosuppressive Therapy be Vaccinated against Influenza Virus? |
| title_full_unstemmed | Should My Patient with Inflammatory Bowel Disease on Immunosuppressive Therapy be Vaccinated against Influenza Virus? |
| title_short | Should My Patient with Inflammatory Bowel Disease on Immunosuppressive Therapy be Vaccinated against Influenza Virus? |
| title_sort | should my patient with inflammatory bowel disease on immunosuppressive therapy be vaccinated against influenza virus |
| url | http://dx.doi.org/10.1155/2010/375878 |
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