Safe and Efficacious Use of Low‐Dose Rituximab in Postpubertal Paediatric Patients With Immune Thrombocytopenia

ABSTRACT Background Rituximab, a CD20 monoclonal antibody, is used in chronic/refractory immune thrombocytopenia (ITP). Standard dosing is 375 mg/m2 weekly for 4 weeks alongside dexamethasone. A lower dose of Rituximab at 100 mg weekly demonstrates comparable efficacy that is well tolerated. This st...

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Bibliographic Details
Main Authors: Jennifer Darlow, Gerard Gurumurthy, Nathan Jeffreys, Lianna Reynolds, Vismay Deshani, John Grainger
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:eJHaem
Online Access:https://doi.org/10.1002/jha2.70010
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