Revealing the Mechanisms of Shikonin Against Diabetic Wounds: A Combined Network Pharmacology and In Vitro Investigation
Conclusion: This study initially revealed the molecular mechanism of SHK in DW by multitarget and multipathway. The PI3K–AKT signaling pathway, MAPK signaling pathway, and AGE-RAGE signaling pathways may be the main pathways of SHK in treating DW.
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
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| Series: | Journal of Diabetes Research |
| Online Access: | http://dx.doi.org/10.1155/jdr/4656485 |
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| Summary: | Conclusion: This study initially revealed the molecular mechanism of SHK in DW by multitarget and multipathway. The PI3K–AKT signaling pathway, MAPK signaling pathway, and AGE-RAGE signaling pathways may be the main pathways of SHK in treating DW. |
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| ISSN: | 2314-6753 |