Priapism in Antipsychotic Drug Use: A Rare but Important Side Effect
Priapism is a rare but important side effect of antipsychotic drugs which may evolve into a urological emergency. Most antipsychotic drugs are alpha-1 adrenergic antagonists, which is thought to be the principal mechanism involved in antipsychotic-induced priapism. Other aetiologies exist, however....
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Psychiatry |
| Online Access: | http://dx.doi.org/10.1155/2012/496364 |
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| author | Igne Sinkeviciute Rune A. Kroken Erik Johnsen |
| author_facet | Igne Sinkeviciute Rune A. Kroken Erik Johnsen |
| author_sort | Igne Sinkeviciute |
| collection | DOAJ |
| description | Priapism is a rare but important side effect of antipsychotic drugs which may evolve into a urological emergency. Most antipsychotic drugs are alpha-1 adrenergic antagonists, which is thought to be the principal mechanism involved in antipsychotic-induced priapism. Other aetiologies exist, however. A case is presented with multiple episodes of priapism during the use of several different antipsychotic drugs. The case is representative of many patients treated with antipsychotic drugs, as there were hyperprolactinemia, and illicit drug use, which are known causes of priapism. Moreover, the patient used combinations of antipsychotic drugs. The case thus illustrates the etiological complexity which could delay a diagnosis of antipsychotic-induced priapism, and the problem of establishing a link between priapism and one particular ingredient of a drug combination. The case presents how a treatment regimen was finally established balancing antipsychotic efficacy to acceptable side effects and offers guidance to physicians regarding how antipsychotic-induced priapism may be resolved. |
| format | Article |
| id | doaj-art-44907acb78644cf9b9f2620f9a6b92cb |
| institution | Kabale University |
| issn | 2090-682X 2090-6838 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Psychiatry |
| spelling | doaj-art-44907acb78644cf9b9f2620f9a6b92cb2025-02-03T01:09:43ZengWileyCase Reports in Psychiatry2090-682X2090-68382012-01-01201210.1155/2012/496364496364Priapism in Antipsychotic Drug Use: A Rare but Important Side EffectIgne Sinkeviciute0Rune A. Kroken1Erik Johnsen2Division of Psychiatry, Haukeland University Hospital, Sandviksleitet 1, 5035 Bergen, NorwayDivision of Psychiatry, Haukeland University Hospital, Sandviksleitet 1, 5035 Bergen, NorwayDivision of Psychiatry, Haukeland University Hospital, Sandviksleitet 1, 5035 Bergen, NorwayPriapism is a rare but important side effect of antipsychotic drugs which may evolve into a urological emergency. Most antipsychotic drugs are alpha-1 adrenergic antagonists, which is thought to be the principal mechanism involved in antipsychotic-induced priapism. Other aetiologies exist, however. A case is presented with multiple episodes of priapism during the use of several different antipsychotic drugs. The case is representative of many patients treated with antipsychotic drugs, as there were hyperprolactinemia, and illicit drug use, which are known causes of priapism. Moreover, the patient used combinations of antipsychotic drugs. The case thus illustrates the etiological complexity which could delay a diagnosis of antipsychotic-induced priapism, and the problem of establishing a link between priapism and one particular ingredient of a drug combination. The case presents how a treatment regimen was finally established balancing antipsychotic efficacy to acceptable side effects and offers guidance to physicians regarding how antipsychotic-induced priapism may be resolved.http://dx.doi.org/10.1155/2012/496364 |
| spellingShingle | Igne Sinkeviciute Rune A. Kroken Erik Johnsen Priapism in Antipsychotic Drug Use: A Rare but Important Side Effect Case Reports in Psychiatry |
| title | Priapism in Antipsychotic Drug Use: A Rare but Important Side Effect |
| title_full | Priapism in Antipsychotic Drug Use: A Rare but Important Side Effect |
| title_fullStr | Priapism in Antipsychotic Drug Use: A Rare but Important Side Effect |
| title_full_unstemmed | Priapism in Antipsychotic Drug Use: A Rare but Important Side Effect |
| title_short | Priapism in Antipsychotic Drug Use: A Rare but Important Side Effect |
| title_sort | priapism in antipsychotic drug use a rare but important side effect |
| url | http://dx.doi.org/10.1155/2012/496364 |
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