Immunogenic cell death-related biomarkers in heart failure probed by transcriptome and single-cell sequencing

Immunogenic cell death-related biomarkers in heart failure probed by transcriptome and single-cell sequencing

BackgroundHeart failure (HF) represents the terminal stage of various cardiovascular disorders, with immunogenic cell death (ICD) potentially influencing HF progression through modulation of immune cell activity. This study aimed to identify ICD-associated biomarkers in patients with HF and explore...

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Bibliographic Details
Main Authors: Haoyue Wang, Dongdong Wu, Gangfei Han, Jingjing Yan, Zehui Wang, Xing He, Yuxiang Chen, Yan Wang, Qinghua Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
immunogenic cell death
heart failure
biomarker
single-cell RNA sequencing analysis
monocytes and macrophages
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1560903/full
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