Creatine monohydrate pilot in Alzheimer's: Feasibility, brain creatine, and cognition

Creatine monohydrate pilot in Alzheimer's: Feasibility, brain creatine, and cognition

Abstract BACKGROUND Preclinical studies suggest that creatine monohydrate (CrM) improves cognition and Alzheimer's disease (AD) biomarkers. However, there is currently no clinical evidence demonstrating the effects of CrM in patients with AD. METHODS In this single‐arm pilot trial, we investiga...

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Bibliographic Details
Main Authors: Aaron N. Smith, In‐Young Choi, Phil Lee, Debra K. Sullivan, Jeffrey M. Burns, Russell H. Swerdlow, Emma Kelly, Matthew K. Taylor
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Subjects:
Alzheimer's disease
bioenergetics
brain creatine
cognition
creatine monohydrate
magnetic resonance spectroscopy
Online Access:https://doi.org/10.1002/trc2.70101
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https://doi.org/10.1002/trc2.70101

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