Multi-Omics Perspectives on Testicular Aging: Unraveling Germline Dysregulation, Niche Dysfunction, and Epigenetic Remodeling
Male reproductive aging proceeds gradually and involves complex alterations across germ cells, somatic cells, and the testicular niche. Multi-omics analyses highlight shifts in spermatogonial stem cell dynamics, diminished sperm quantity and quality, and reconfigured support from Sertoli and Leydig...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-06-01
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| Series: | Cells |
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| Online Access: | https://www.mdpi.com/2073-4409/14/12/899 |
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