Development of ultra-short PCR assay to reveal BRAF V600 mutation status in Thai colorectal cancer tissues.

Development of ultra-short PCR assay to reveal BRAF V600 mutation status in Thai colorectal cancer tissues.

The protein kinase BRAF is one of the key players in regulating cellular responses to extracellular signals. Somatic mutations of the BRAF gene, causing constitutive activation of BRAF, have been found in various types of human cancers such as malignant melanoma, and colorectal cancer. BRAF V600E an...

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Main Authors: Nunthawut Chat-Uthai, Pichpisith Vejvisithsakul, Sutthirat Udommethaporn, Puttarakun Meesiri, Chetiya Danthanawanit, Yannawan Wongchai, Chinachote Teerapakpinyo, Shanop Shuangshoti, Naravat Poungvarin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pone.0198795/1/pone.0198795.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210221%2Fauto%2Fstorage%2Fgoog4_request&X-Goog-Date=20210221T134639Z&X-Goog-Expires=3600&X-Goog-SignedHeaders=host&X-Goog-Signature=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