血清miR-491-5p和miR-21-5p对急性缺血性卒中患者静脉溶栓后出血转化的预测价值 Predictive Value of Serum miR-491-5p and miR-21-5p on Hemorrhagic Transformation after Intravenous Thrombolysis in Acute Ischemic Stroke Patients
目的 探讨血清微小RNA(microRNA,miRNA/miR)中miR-491-5p、miR-21-5p对急性缺血性卒中(acute ischemic stroke,AIS)患者静脉溶栓后出血转化的预测价值。 方法 回顾性选取2021年1月—2023年2月南阳市中心医院收治的312例AIS静脉溶栓治疗患者为研究对象,按照静脉溶栓后24 h内出血转化发生情况分为出血转化组(66例)和非出血转化组(246例)。实时荧光定量PCR测定血清miR-491-5p、miR-21-5p表达水平。采用多因素logistic回归分析探讨AIS患者静脉溶栓后出血转化的独立危险因素,以ROC曲线分析血清miR-...
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| Main Author: | 王笑寒1,潘燕1,张小林1,刘坦2 (WANG Xiaohan1, PAN Yan1, ZHANG Xiaolin1, LIU Tan2 ) |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Chinese Journal of Stroke
2024-12-01
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| Series: | Zhongguo cuzhong zazhi |
| Subjects: | |
| Online Access: | https://www.chinastroke.org.cn/CN/10.3969/j.issn.1673-5765.2024.12.011 |
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