Tegaserod maleate exerts anti-tumor effects on prostate cancer via repressing sonic hedgehog signaling pathway

Tegaserod maleate exerts anti-tumor effects on prostate cancer via repressing sonic hedgehog signaling pathway

Abstract Prostate cancer (PCa) is a highly common type of malignancy and affects millions of men in the world since it is easy to recur or emerge therapy resistance. Therefore, it is urgent to find novel treatments for PCa patients. In the current study, we found that tegaserod maleate (TM), an FDA-...

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Bibliographic Details
Main Authors: Maoping Cai, Shengdong Ge, Yaying Hong, Yao Chen, Yang-Zi Ren, Dacai Zhong, Mingkun Chen, Yuan Liu, Zhe-Sheng Chen, Ninghan Feng, Zhanghui Chen, Shan-Chao Zhao
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Molecular Medicine
Subjects:
Prostate cancer (PCa)
Tegaserod maleate (TM)
Sonic hedgehog (SHH) signaling
GLI2
Treatment
Online Access:https://doi.org/10.1186/s10020-025-01080-1
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https://doi.org/10.1186/s10020-025-01080-1

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