Waning immunity, prevailing non-vaccine type ptxP3 and macrolide-resistant strains in the 2024 pertussis outbreak in China: a multicentre cross-sectional descriptive studyResearch in context

Waning immunity, prevailing non-vaccine type ptxP3 and macrolide-resistant strains in the 2024 pertussis outbreak in China: a multicentre cross-sectional descriptive studyResearch in context

Summary: Background: In the spring and summer of 2024, an unexpected large outbreak of pertussis hit China, with the annual incidence of pertussis (34.03/100,000) more than 12-fold higher than that of 2023 (2.71/100,000). We aimed to assess clinical and molecular epidemiological patterns and unrave...

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Main Authors: Jiehao Cai, Qiyi Liu, Biquan Chen, Yue Jiang, Xiaoyan Zeng, Jiebin Huang, Daojiong Lin, Huanyou Li, Jinqiang Zhang, Zhiqiang Zhuo, Yanping Zhang, Panpan Lv, Qiang Wang, Wenhong Zhang, Mingliang Chen, Mei Zeng
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:The Lancet Regional Health. Western Pacific
Subjects:
Bordetella pertussis
Outbreak
Azithromycin-resistant
ptxP3
PRN-deficiency
Whole genome sequence
Online Access:http://www.sciencedirect.com/science/article/pii/S2666606525001658
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