Exploring peripheral fluid biomarkers for early detection of Alzheimer's disease in Down syndrome: A literature review

People with Down Syndrome (DS) are at high risk of developing Alzheimer's disease dementia (AD) and cerebral amyloid angiopathy, which is a critical factor contributing to dementia in sporadic AD. Predicting and monitoring the decline and onset of dementia is a diagnostic challenge and of essen...

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Bibliographic Details
Main Authors: Charlotte Jacob, Marleen Tollenaere, Hanane Kachar, Marie-Claude Potier, Peter Paul De Deyn, Debby Van Dam
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Heliyon
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Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024174762
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