Analysis of serum levels and DNA methylation of fibroblast growth factor 21 using peripheral blood-derived genomes in patients with obesity

Analysis of serum levels and DNA methylation of fibroblast growth factor 21 using peripheral blood-derived genomes in patients with obesity

Fibroblast growth factor (FGF) 21, a hormone produced by the liver, improves glucose and lipid metabolism. We recently demonstrated that the FGF21 gene (Fgf21) underwent DNA demethylation in the mouse liver via peroxisome proliferator-activated receptor (PPAR) α during the fetal to lactation periods...

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Bibliographic Details
Main Authors: Hiroyuki Shinozaki, Shiori Kawai, Mami Gamo-Kawasaki, Ayano Takei, Kyoko Tsujikado, Kazunori Fukuda, Mototaka Yamauchi, Kenji Hara, Takafumi Tsuchiya, Kohzo Takebayashi, Koshi Hashimoto
Format: Article
Language:English
Published: The Japan Endocrine Society 2024-09-01
Series:Endocrine Journal
Subjects:
obesity
fibroblast growth factor (fgf) 21
dna methylation
pemafibrate (pm)
Online Access:https://www.jstage.jst.go.jp/article/endocrj/71/9/71_EJ23-0570/_html/-char/en
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