Physiology-informed regularisation enables training of universal differential equation systems for biological applications.

Systems biology tackles the challenge of understanding the high complexity in the internal regulation of homeostasis in the human body through mathematical modelling. These models can aid in the discovery of disease mechanisms and potential drug targets. However, on one hand the development and vali...

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Bibliographic Details
Main Authors: Max de Rooij, Balázs Erdős, Natal A W van Riel, Shauna D O'Donovan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1012198
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