Recurrence of atrial fibrillation and late cardiovascular events in patients with persistent atrial fibrillation after restoration of sinus rhythm
The aim – to study the role of late recurrences of AF in predicting adverse course of the disease in patients with persistent AF after cardioversion at 9-month follow-up. Material and methods. The study included 120 patients with documented persistent AF who underwent successful cardioversion dur...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
TOV Chetverta Khvylia
2020-06-01
|
| Series: | Кардіохірургія та інтервенційна кардіологія |
| Subjects: | |
| Online Access: | http://csic.com.ua/images/pdf/2020/2-2020/recurrence-atrial-fibrillation-late-cardiovascular-events-in-patients-with-persistent-atrial-fibrillation-after-restoration-of-sinus-rhythm.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832564464794206208 |
|---|---|
| author | U.P. Chernyaha-Royko N.S. Pavlyk M.S. Sorokivskyy A.V. Aker O.J. Zharinov |
| author_facet | U.P. Chernyaha-Royko N.S. Pavlyk M.S. Sorokivskyy A.V. Aker O.J. Zharinov |
| author_sort | U.P. Chernyaha-Royko |
| collection | DOAJ |
| description | The aim – to study the role of late recurrences of AF in predicting adverse course of the disease in patients with persistent AF after cardioversion at 9-month follow-up.
Material and methods. The study included 120 patients with documented persistent AF who underwent successful cardioversion during hospitalization. After discharge patients were followed up for 9 months. Demographic and clinical-functional features, data of event monitoring (EV) for 7 days and Holter monitoring (HM ECG), treatment were compared in groups of patients with (n = 15) and without (n = 105) events.
Results. During 9-month follow-up, 15 (12.5 %) of 120 patients developed cardiovascular events: death (n = 1), stroke (n = 2), other thromboischemic events (n = 3), myocardial infarction (n = 1), decompensated heart failure (n = 4) and left ventricular ejection fraction (LVEF) reduction 10 % or more (n = 9). Patients with and without events had no significant differences in age, gender, weight, risk factors, HM ECG data and background pathology. Patients with events had a higher risk of CHA2DS2-VASc (p = 0.05), lower LV EF (p = 0.00009), more symptomatic recurrence of AF (p = 0.08), ventricular arrhythmias (p = 0.08) and short-run atrial tachyarrhythmia lasting up to 30 seconds (p = 0.05) according to EM; AF more often turned into permanent form (p = 0.002). Patients with events were more likely to receive digoxin (p = 0.04).
Conclusions. The main differences between patients with persistent AF after successful recovery of the sinus rhythm, in which events occurred within 9 months, were: higher score on the scale CHA2DS2-VASc, lower LV EF, more frequent presence of late recurrences of AF, including transition to a permanent form, more frequent short-term paroxysms of atrial tachyarrhythmias during EM after 9 months of observation, as well as the use of digoxin |
| format | Article |
| id | doaj-art-432982e1c73a4aef96aa38ad4f09a9bf |
| institution | Kabale University |
| issn | 2305-3127 |
| language | English |
| publishDate | 2020-06-01 |
| publisher | TOV Chetverta Khvylia |
| record_format | Article |
| series | Кардіохірургія та інтервенційна кардіологія |
| spelling | doaj-art-432982e1c73a4aef96aa38ad4f09a9bf2025-02-03T01:10:52ZengTOV Chetverta KhvyliaКардіохірургія та інтервенційна кардіологія2305-31272020-06-0122835http://doi.org/10.31928/2305-3127-2020.2.2835Recurrence of atrial fibrillation and late cardiovascular events in patients with persistent atrial fibrillation after restoration of sinus rhythmU.P. Chernyaha-Royko0N.S. Pavlyk1M.S. Sorokivskyy2A.V. Aker3O.J. Zharinov4Danylo Halytsky Lviv National Medical University, Lviv, UkraineLviv Regional Cardiology Center, Ukraine, Lviv, UkraineDanylo Halytsky Lviv National Medical University, Lviv, UkraineLviv Regional Cardiology Center, Ukraine, Lviv, UkraineShupyk National Medical Academy of Postgraduate Education, Kyiv, UkraineThe aim – to study the role of late recurrences of AF in predicting adverse course of the disease in patients with persistent AF after cardioversion at 9-month follow-up. Material and methods. The study included 120 patients with documented persistent AF who underwent successful cardioversion during hospitalization. After discharge patients were followed up for 9 months. Demographic and clinical-functional features, data of event monitoring (EV) for 7 days and Holter monitoring (HM ECG), treatment were compared in groups of patients with (n = 15) and without (n = 105) events. Results. During 9-month follow-up, 15 (12.5 %) of 120 patients developed cardiovascular events: death (n = 1), stroke (n = 2), other thromboischemic events (n = 3), myocardial infarction (n = 1), decompensated heart failure (n = 4) and left ventricular ejection fraction (LVEF) reduction 10 % or more (n = 9). Patients with and without events had no significant differences in age, gender, weight, risk factors, HM ECG data and background pathology. Patients with events had a higher risk of CHA2DS2-VASc (p = 0.05), lower LV EF (p = 0.00009), more symptomatic recurrence of AF (p = 0.08), ventricular arrhythmias (p = 0.08) and short-run atrial tachyarrhythmia lasting up to 30 seconds (p = 0.05) according to EM; AF more often turned into permanent form (p = 0.002). Patients with events were more likely to receive digoxin (p = 0.04). Conclusions. The main differences between patients with persistent AF after successful recovery of the sinus rhythm, in which events occurred within 9 months, were: higher score on the scale CHA2DS2-VASc, lower LV EF, more frequent presence of late recurrences of AF, including transition to a permanent form, more frequent short-term paroxysms of atrial tachyarrhythmias during EM after 9 months of observation, as well as the use of digoxinhttp://csic.com.ua/images/pdf/2020/2-2020/recurrence-atrial-fibrillation-late-cardiovascular-events-in-patients-with-persistent-atrial-fibrillation-after-restoration-of-sinus-rhythm.pdfpersistent atrial fibrillationrelapsescardiovascular complications |
| spellingShingle | U.P. Chernyaha-Royko N.S. Pavlyk M.S. Sorokivskyy A.V. Aker O.J. Zharinov Recurrence of atrial fibrillation and late cardiovascular events in patients with persistent atrial fibrillation after restoration of sinus rhythm Кардіохірургія та інтервенційна кардіологія persistent atrial fibrillation relapses cardiovascular complications |
| title | Recurrence of atrial fibrillation and late cardiovascular events in patients with persistent atrial fibrillation after restoration of sinus rhythm |
| title_full | Recurrence of atrial fibrillation and late cardiovascular events in patients with persistent atrial fibrillation after restoration of sinus rhythm |
| title_fullStr | Recurrence of atrial fibrillation and late cardiovascular events in patients with persistent atrial fibrillation after restoration of sinus rhythm |
| title_full_unstemmed | Recurrence of atrial fibrillation and late cardiovascular events in patients with persistent atrial fibrillation after restoration of sinus rhythm |
| title_short | Recurrence of atrial fibrillation and late cardiovascular events in patients with persistent atrial fibrillation after restoration of sinus rhythm |
| title_sort | recurrence of atrial fibrillation and late cardiovascular events in patients with persistent atrial fibrillation after restoration of sinus rhythm |
| topic | persistent atrial fibrillation relapses cardiovascular complications |
| url | http://csic.com.ua/images/pdf/2020/2-2020/recurrence-atrial-fibrillation-late-cardiovascular-events-in-patients-with-persistent-atrial-fibrillation-after-restoration-of-sinus-rhythm.pdf |
| work_keys_str_mv | AT upchernyaharoyko recurrenceofatrialfibrillationandlatecardiovasculareventsinpatientswithpersistentatrialfibrillationafterrestorationofsinusrhythm AT nspavlyk recurrenceofatrialfibrillationandlatecardiovasculareventsinpatientswithpersistentatrialfibrillationafterrestorationofsinusrhythm AT mssorokivskyy recurrenceofatrialfibrillationandlatecardiovasculareventsinpatientswithpersistentatrialfibrillationafterrestorationofsinusrhythm AT avaker recurrenceofatrialfibrillationandlatecardiovasculareventsinpatientswithpersistentatrialfibrillationafterrestorationofsinusrhythm AT ojzharinov recurrenceofatrialfibrillationandlatecardiovasculareventsinpatientswithpersistentatrialfibrillationafterrestorationofsinusrhythm |