Mesoscopic Structure of Lipid Nanoparticles Studied by Small-Angle X-Ray Scattering: A Spherical Core-Triple Shell Model Analysis

Lipid nanoparticles (LNPs) are widely recognized as effective drug delivery systems for RNA therapeutics because their efficacy is critically dependent on structural organization. The mesoscopic architecture of these multicomponent systems, which is governed by interactions among ionizable lipids, s...

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Bibliographic Details
Main Authors: Hao Li, Panqi Song, Yiwen Li, Shuyang Tu, Mehwish Mehmood, Liang Chen, Na Li, Qiang Tian
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Membranes
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Online Access:https://www.mdpi.com/2077-0375/15/5/153
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