Novel N-quaternary coumarin-3-yl-imidazo[1,2-a]pyridines as fluorescent hybrids: Their synthesis and biological evaluation in cancer cells

Novel N-quaternary coumarin-3-yl-imidazo[1,2-a]pyridines as fluorescent hybrids: Their synthesis and biological evaluation in cancer cells

Hybrid coumarin-3-yl-imidazo[1,2-a]pyridines were used to synthesize novel derivatives of quaternary salts 5a-c and 6a,b, employing ethyl iodide and benzyl bromide as alkylating agents. The molecular patterns of Total Polar Surface Area (TPSA) coincide with substituent polarity at positions 6 or 7,...

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Main Authors: Karla Armendariz-Barrientos, Luis A. Pérez, Selene Lagunas-Rivera, Yolanda Alcaraz-Contreras, Marco A. García-Revilla, Heriberto Prado-Garcia, Rocío García-Becerra, Miguel A. Vazquez
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Results in Chemistry
Subjects:
N-quaternary coumarin-3-yl-imidazo[1
2-a]pyridines hybrids
Chromophores
Fluorescent detection
Antiproliferative activity
ADMED analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715624006556
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