Modeling PROTAC degradation activity with machine learning
PROTACs are a promising therapeutic modality that harnesses the cell’s built-in degradation machinery to degrade specific proteins. Despite their potential, developing new PROTACs is challenging and requires significant domain expertise, time, and cost. Meanwhile, machine learning has transformed dr...
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| Main Authors: | Stefano Ribes, Eva Nittinger, Christian Tyrchan, Rocío Mercado |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-12-01
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| Series: | Artificial Intelligence in the Life Sciences |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667318524000114 |
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