Renal Anemia Control in Lithuania: Influence of Local Conditions and Local Guidelines

Erythropoietin stimulating agents had a long haul in Lithuania—we had no epoetin till 1994 and there was no intravenous iron in 2001–2004. The aim of this study was to assess the changes of renal anemia control in hemodialysis patients from early independence of Lithuania till nowadays and to evalu...

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Main Authors: Edita Ziginskiene, Vytautas Kuzminskis, Kristina Petruliene, Ruta Vaiciuniene, Asta Stankuviene, Inga Arune Bumblyte
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2013/260915
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author Edita Ziginskiene
Vytautas Kuzminskis
Kristina Petruliene
Ruta Vaiciuniene
Asta Stankuviene
Inga Arune Bumblyte
author_facet Edita Ziginskiene
Vytautas Kuzminskis
Kristina Petruliene
Ruta Vaiciuniene
Asta Stankuviene
Inga Arune Bumblyte
author_sort Edita Ziginskiene
collection DOAJ
description Erythropoietin stimulating agents had a long haul in Lithuania—we had no epoetin till 1994 and there was no intravenous iron in 2001–2004. The aim of this study was to assess the changes of renal anemia control in hemodialysis patients from early independence of Lithuania till nowadays and to evaluate the link of anemia with hospitalization rates and survival and hemoglobin variability in association with mortality. In December of each year since 1996 all hemodialysis centers have been visited and data has been collected using special questionnaires. The history of renal anemia control in Lithuania was complicated; however, a significant improvement was achieved: 54.7% of hemodialysis patients reached the target hemoglobin; all patients have a possibility of treatment with epoetin and intravenous iron. The involuntary experiment with an intravenous iron occurred in Lithuania because of economic reasons and confirmed the significant role of intravenous iron in the management of renal anemia. Hemoglobin below 100 g/L was associated with a 2.5-fold increase in relative risk of death and 1.7-fold increase in relative risk of hospitalization in Lithuanian hemodialysis patients. Although hemoglobin variability was common in Lithuanian hemodialysis patients, we did not find the association between hemoglobin variability and all-cause mortality in our study.
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issn 1537-744X
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spelling doaj-art-42c94af1ce3b43919b36ea16b610fba82025-02-03T06:11:17ZengWileyThe Scientific World Journal1537-744X2013-01-01201310.1155/2013/260915260915Renal Anemia Control in Lithuania: Influence of Local Conditions and Local GuidelinesEdita Ziginskiene0Vytautas Kuzminskis1Kristina Petruliene2Ruta Vaiciuniene3Asta Stankuviene4Inga Arune Bumblyte5Department of Nephrology, Medical Academy, Lithuanian University of Health Sciences, Mickeviciaus str. 9, LT-44307 Kaunas, LithuaniaDepartment of Nephrology, Medical Academy, Lithuanian University of Health Sciences, Mickeviciaus str. 9, LT-44307 Kaunas, LithuaniaDepartment of Nephrology, Medical Academy, Lithuanian University of Health Sciences, Mickeviciaus str. 9, LT-44307 Kaunas, LithuaniaDepartment of Nephrology, Medical Academy, Lithuanian University of Health Sciences, Mickeviciaus str. 9, LT-44307 Kaunas, LithuaniaDepartment of Nephrology, Medical Academy, Lithuanian University of Health Sciences, Mickeviciaus str. 9, LT-44307 Kaunas, LithuaniaDepartment of Nephrology, Medical Academy, Lithuanian University of Health Sciences, Mickeviciaus str. 9, LT-44307 Kaunas, LithuaniaErythropoietin stimulating agents had a long haul in Lithuania—we had no epoetin till 1994 and there was no intravenous iron in 2001–2004. The aim of this study was to assess the changes of renal anemia control in hemodialysis patients from early independence of Lithuania till nowadays and to evaluate the link of anemia with hospitalization rates and survival and hemoglobin variability in association with mortality. In December of each year since 1996 all hemodialysis centers have been visited and data has been collected using special questionnaires. The history of renal anemia control in Lithuania was complicated; however, a significant improvement was achieved: 54.7% of hemodialysis patients reached the target hemoglobin; all patients have a possibility of treatment with epoetin and intravenous iron. The involuntary experiment with an intravenous iron occurred in Lithuania because of economic reasons and confirmed the significant role of intravenous iron in the management of renal anemia. Hemoglobin below 100 g/L was associated with a 2.5-fold increase in relative risk of death and 1.7-fold increase in relative risk of hospitalization in Lithuanian hemodialysis patients. Although hemoglobin variability was common in Lithuanian hemodialysis patients, we did not find the association between hemoglobin variability and all-cause mortality in our study.http://dx.doi.org/10.1155/2013/260915
spellingShingle Edita Ziginskiene
Vytautas Kuzminskis
Kristina Petruliene
Ruta Vaiciuniene
Asta Stankuviene
Inga Arune Bumblyte
Renal Anemia Control in Lithuania: Influence of Local Conditions and Local Guidelines
The Scientific World Journal
title Renal Anemia Control in Lithuania: Influence of Local Conditions and Local Guidelines
title_full Renal Anemia Control in Lithuania: Influence of Local Conditions and Local Guidelines
title_fullStr Renal Anemia Control in Lithuania: Influence of Local Conditions and Local Guidelines
title_full_unstemmed Renal Anemia Control in Lithuania: Influence of Local Conditions and Local Guidelines
title_short Renal Anemia Control in Lithuania: Influence of Local Conditions and Local Guidelines
title_sort renal anemia control in lithuania influence of local conditions and local guidelines
url http://dx.doi.org/10.1155/2013/260915
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AT kristinapetruliene renalanemiacontrolinlithuaniainfluenceoflocalconditionsandlocalguidelines
AT rutavaiciuniene renalanemiacontrolinlithuaniainfluenceoflocalconditionsandlocalguidelines
AT astastankuviene renalanemiacontrolinlithuaniainfluenceoflocalconditionsandlocalguidelines
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