Simulation of Mechanical Heart Valve Dysfunction and the Non-Newtonian Blood Model Approach
The mechanical heart valve (MHV) is commonly used for the treatment of cardiovascular diseases. Nonphysiological hemodynamic in the MHV may cause hemolysis, platelet activation, and an increased risk of thromboembolism. Thromboembolism may cause severe complications and valve dysfunction. This paper...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Applied Bionics and Biomechanics |
| Online Access: | http://dx.doi.org/10.1155/2022/9612296 |
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| author | Aolin Chen Adi Azriff Bin Basri Norzian Bin Ismail Masaaki Tamagawa Di Zhu Kamarul Arifin Ahmad |
| author_facet | Aolin Chen Adi Azriff Bin Basri Norzian Bin Ismail Masaaki Tamagawa Di Zhu Kamarul Arifin Ahmad |
| author_sort | Aolin Chen |
| collection | DOAJ |
| description | The mechanical heart valve (MHV) is commonly used for the treatment of cardiovascular diseases. Nonphysiological hemodynamic in the MHV may cause hemolysis, platelet activation, and an increased risk of thromboembolism. Thromboembolism may cause severe complications and valve dysfunction. This paper thoroughly reviewed the simulation of physical quantities (velocity distribution, vortex formation, and shear stress) in healthy and dysfunctional MHV and reviewed the non-Newtonian blood flow characteristics in MHV. In the MHV numerical study, the dysfunction will affect the simulation results, increase the pressure gradient and shear stress, and change the blood flow patterns, increasing the risks of hemolysis and platelet activation. The blood flow passes downstream and has obvious recirculation and stagnation region with the increased dysfunction severity. Due to the complex structure of the MHV, the non-Newtonian shear-thinning viscosity blood characteristics become apparent in MHV simulations. The comparative study between Newtonian and non-Newtonian always shows the difference. The shear-thinning blood viscosity model is the basics to build the blood, also the blood exhibiting viscoelastic properties. More details are needed to establish a complete and more realistic simulation. |
| format | Article |
| id | doaj-art-42b8370cc66d4cda9e6a8311c9acfdc3 |
| institution | Kabale University |
| issn | 1754-2103 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Applied Bionics and Biomechanics |
| spelling | doaj-art-42b8370cc66d4cda9e6a8311c9acfdc32025-02-03T01:08:47ZengWileyApplied Bionics and Biomechanics1754-21032022-01-01202210.1155/2022/9612296Simulation of Mechanical Heart Valve Dysfunction and the Non-Newtonian Blood Model ApproachAolin Chen0Adi Azriff Bin Basri1Norzian Bin Ismail2Masaaki Tamagawa3Di Zhu4Kamarul Arifin Ahmad5Faculty of EngineeringFaculty of EngineeringFaculty of Medicine and Health SciencesGraduate School of Life Science and Systems EngineeringFaculty of EngineeringFaculty of EngineeringThe mechanical heart valve (MHV) is commonly used for the treatment of cardiovascular diseases. Nonphysiological hemodynamic in the MHV may cause hemolysis, platelet activation, and an increased risk of thromboembolism. Thromboembolism may cause severe complications and valve dysfunction. This paper thoroughly reviewed the simulation of physical quantities (velocity distribution, vortex formation, and shear stress) in healthy and dysfunctional MHV and reviewed the non-Newtonian blood flow characteristics in MHV. In the MHV numerical study, the dysfunction will affect the simulation results, increase the pressure gradient and shear stress, and change the blood flow patterns, increasing the risks of hemolysis and platelet activation. The blood flow passes downstream and has obvious recirculation and stagnation region with the increased dysfunction severity. Due to the complex structure of the MHV, the non-Newtonian shear-thinning viscosity blood characteristics become apparent in MHV simulations. The comparative study between Newtonian and non-Newtonian always shows the difference. The shear-thinning blood viscosity model is the basics to build the blood, also the blood exhibiting viscoelastic properties. More details are needed to establish a complete and more realistic simulation.http://dx.doi.org/10.1155/2022/9612296 |
| spellingShingle | Aolin Chen Adi Azriff Bin Basri Norzian Bin Ismail Masaaki Tamagawa Di Zhu Kamarul Arifin Ahmad Simulation of Mechanical Heart Valve Dysfunction and the Non-Newtonian Blood Model Approach Applied Bionics and Biomechanics |
| title | Simulation of Mechanical Heart Valve Dysfunction and the Non-Newtonian Blood Model Approach |
| title_full | Simulation of Mechanical Heart Valve Dysfunction and the Non-Newtonian Blood Model Approach |
| title_fullStr | Simulation of Mechanical Heart Valve Dysfunction and the Non-Newtonian Blood Model Approach |
| title_full_unstemmed | Simulation of Mechanical Heart Valve Dysfunction and the Non-Newtonian Blood Model Approach |
| title_short | Simulation of Mechanical Heart Valve Dysfunction and the Non-Newtonian Blood Model Approach |
| title_sort | simulation of mechanical heart valve dysfunction and the non newtonian blood model approach |
| url | http://dx.doi.org/10.1155/2022/9612296 |
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