Thyroid Autoimmunity and Behçet’s Disease: Is There a Significant Association?
Background. Behcet’s disease (BD) could be regarded as an autoimmune disease in many aspects. Autoimmune thyroid disease (ATD) is frequently accompanied by other various autoimmune diseases. Nevertheless, there is not still enough data showing the association between BD and ATD. In addition, no cont...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2013/956837 |
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| author | Filiz Cebeci Nahide Onsun Ayşe Pekdemir Ahmet R. Uras Kadir Kayataş |
| author_facet | Filiz Cebeci Nahide Onsun Ayşe Pekdemir Ahmet R. Uras Kadir Kayataş |
| author_sort | Filiz Cebeci |
| collection | DOAJ |
| description | Background. Behcet’s disease (BD) could be regarded as an autoimmune disease in many aspects. Autoimmune thyroid disease (ATD) is frequently accompanied by other various autoimmune diseases. Nevertheless, there is not still enough data showing the association between BD and ATD. In addition, no controlled study is present in the PubMed, which evaluates thyroidal autoimmunity using antithyroid peroxidase antibody in a large series of patients with BD. Methods. We aimed to investigate the frequency of ATD in patients with BD. The study included 124 patients with BD and 99 age- and sex-matched healthy volunteers. Results. Autoimmune thyroiditis was noted in 21 cases (16.9%) with BD. In the control group, 22 cases (22.22%) were diagnosed as autoimmune thyroiditis. There was no difference between the groups in respect to thyroid autoantibodies (). There were no statistically significant differences between baseline TSH levels of the BD patients and of the controls (). Statistically, the mean serum free T4 levels of the patients with BD were higher than those of the controls (). Conclusions. No association could be found between BD and ATD. Therefore, it is not of significance to investigate thyroid autoimmunity in BD. |
| format | Article |
| id | doaj-art-4279c118e5c74b24b49e56b8c6337356 |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-4279c118e5c74b24b49e56b8c63373562025-02-03T00:59:14ZengWileyThe Scientific World Journal1537-744X2013-01-01201310.1155/2013/956837956837Thyroid Autoimmunity and Behçet’s Disease: Is There a Significant Association?Filiz Cebeci0Nahide Onsun1Ayşe Pekdemir2Ahmet R. Uras3Kadir Kayataş4Department of Dermatology, Haydarpaşa Numune Training and Research Hospital, 34668 İstanbul, TurkeyDepartment of Dermatology, Faculty of Medicine, Bezmialem Vakıf University, İstanbul, TurkeyDepartment of Dermatology, Faculty of Medicine, Bezmialem Vakıf University, İstanbul, TurkeyBiochemistry Laboratory, Haydarpaşa Numune Training and Research Hospital, 34668 İstanbul, TurkeyDepartment of General Medicine, Haydarpaşa Numune Training and Research Hospital, 34668 İstanbul, TurkeyBackground. Behcet’s disease (BD) could be regarded as an autoimmune disease in many aspects. Autoimmune thyroid disease (ATD) is frequently accompanied by other various autoimmune diseases. Nevertheless, there is not still enough data showing the association between BD and ATD. In addition, no controlled study is present in the PubMed, which evaluates thyroidal autoimmunity using antithyroid peroxidase antibody in a large series of patients with BD. Methods. We aimed to investigate the frequency of ATD in patients with BD. The study included 124 patients with BD and 99 age- and sex-matched healthy volunteers. Results. Autoimmune thyroiditis was noted in 21 cases (16.9%) with BD. In the control group, 22 cases (22.22%) were diagnosed as autoimmune thyroiditis. There was no difference between the groups in respect to thyroid autoantibodies (). There were no statistically significant differences between baseline TSH levels of the BD patients and of the controls (). Statistically, the mean serum free T4 levels of the patients with BD were higher than those of the controls (). Conclusions. No association could be found between BD and ATD. Therefore, it is not of significance to investigate thyroid autoimmunity in BD.http://dx.doi.org/10.1155/2013/956837 |
| spellingShingle | Filiz Cebeci Nahide Onsun Ayşe Pekdemir Ahmet R. Uras Kadir Kayataş Thyroid Autoimmunity and Behçet’s Disease: Is There a Significant Association? The Scientific World Journal |
| title | Thyroid Autoimmunity and Behçet’s Disease: Is There a Significant Association? |
| title_full | Thyroid Autoimmunity and Behçet’s Disease: Is There a Significant Association? |
| title_fullStr | Thyroid Autoimmunity and Behçet’s Disease: Is There a Significant Association? |
| title_full_unstemmed | Thyroid Autoimmunity and Behçet’s Disease: Is There a Significant Association? |
| title_short | Thyroid Autoimmunity and Behçet’s Disease: Is There a Significant Association? |
| title_sort | thyroid autoimmunity and behcet s disease is there a significant association |
| url | http://dx.doi.org/10.1155/2013/956837 |
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