The anti-cancerous mechanism of licochalcone A on human hepatoma cell HepG2 based on the miRNA omics

The anti-cancerous mechanism of licochalcone A on human hepatoma cell HepG2 based on the miRNA omics

To explore the function of licochalcone A as an anticancer phytochemical on HepG2 cells and investigate its potential mechanisms, we analyzed the microRNAs (miRNAs) expression profile of HepG2 cells in response to licochalcone A (70 μmol/L) in vitro. 102 dysregulated miRNAs were detected, and SP1 wa...

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Bibliographic Details
Main Authors: Jun Wang, Xiuxiu Zhang, Zhijing Ni, Elnur Elam, Kiran Thakur, Kexin Li, Chuyan Wang, Jianguo Zhang, Zhaojun Wei
Format: Article
Language:English
Published: Tsinghua University Press 2023-07-01
Series:Food Science and Human Wellness
Subjects:
Licochalcone A
HepG2 cells
Dysregulated miRNAs
Transcription factors
Targets
Regulatory networks
Online Access:http://www.sciencedirect.com/science/article/pii/S2213453022002580
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