Genome Editing as a Vehicle to Drive Successful Chimeric Antigen Receptor T Cell Therapies to the Clinic

Chimeric antigen receptor (CAR) T cells have emerged as an effective therapy for patients with relapsed and refractory haematological malignancies. However, there are many challenges preventing clinical efficacy and thus broader translation of this approach. These hurdles include poor autologous T...

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Bibliographic Details
Main Authors: Caitlin R Hopkins, Joseph A Fraietta
Format: Article
Language:English
Published: European Medical Journal 2021-12-01
Series:European Medical Journal
Online Access:https://www.emjreviews.com/hematology/article/genome-editing-as-a-vehicle-to-drive-successful-chimeric-antigen-receptor-t-cell-therapies-to-the-clinic/
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