Synthesis and in silico ADMET evaluation of new thiazole and thiazolidine-4-one derivatives as non-ulcerogenic analgesic and anti-inflammatory agents

A series of 1,3-thiazoline-4-one derivatives bearing 2-phenoxyphenyl moiety, were synthesized as potential new analgesic and anti-inflammatory agents. The structures were confirmed by FT-IR, NMR and mass spectra. The abdominal constriction (writing) test was selected to evaluate analgesic activity a...

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Bibliographic Details
Main Authors: Nassiri Koopaei Mansur, Monavari Mahshid, Vousooghi Nasim, Moshirabadi Sadaf, Assarzadeh Mohammad Javad, Amini Mohsen, Almasirad Ali
Format: Article
Language:English
Published: Serbian Chemical Society 2024-01-01
Series:Journal of the Serbian Chemical Society
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Online Access:https://doiserbia.nb.rs/img/doi/0352-5139/2024/0352-51392400064N.pdf
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