Improvement of D-lactic acid production from methanol by metabolically engineered Komagataella phaffii via ultra-violet mutagenesis

Improvement of D-lactic acid production from methanol by metabolically engineered Komagataella phaffii via ultra-violet mutagenesis

Methanol has attracted attention as an alternative carbon source to petroleum. Komagataella phaffii, a methanol-assimilating yeast, is a useful host for the chemical production from methanol. A previous study successfully constructed a metabolically engineered K. phaffii GS115/S8/Z3 strain capable o...

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Bibliographic Details
Main Authors: Yoshifumi Inoue, Kaito Nakamura, Ryosuke Yamada, Takuya Matsumoto, Hiroyasu Ogino
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Metabolic Engineering Communications
Subjects:
D-lactic acid
Komagataella phaffii
Methanol
Ultra-violet mutagenesis
Transcriptome analysis
Yeast
Online Access:http://www.sciencedirect.com/science/article/pii/S2214030125000069
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