Malignant Transformation of Mature Cystic Teratoma Diagnosed after a 10-Year Interval

A 67-year-old uniparous woman had undergone surgery for acute perforated gastric ulcer 10 years prior to the current presentation. Although abdominal computed tomography (CT) performed at that point had revealed a mature cystic teratoma measuring 6 cm in diameter in the right ovary, it was left untr...

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Main Authors: Mariko Jitsumori, Satoru Munakata, Toshiya Yamamoto
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2017/2947927
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author Mariko Jitsumori
Satoru Munakata
Toshiya Yamamoto
author_facet Mariko Jitsumori
Satoru Munakata
Toshiya Yamamoto
author_sort Mariko Jitsumori
collection DOAJ
description A 67-year-old uniparous woman had undergone surgery for acute perforated gastric ulcer 10 years prior to the current presentation. Although abdominal computed tomography (CT) performed at that point had revealed a mature cystic teratoma measuring 6 cm in diameter in the right ovary, it was left untreated. She visited the department of surgery at our hospital with chief complaints of appetite loss, nausea, and vomiting that had persisted for the prior two weeks. She was admitted with a diagnosis of ileus attributed to an abdominal incisional hernia. CT performed on admission revealed a tumor measuring 21 cm in diameter with mural nodules in the right ovary. Thus, surgery was performed under suspicion of malignant transformation of the previously detected ovarian mature cystic teratoma. While neither lymphadenopathy nor distant metastasis was detected by imaging studies, bilateral adnexectomy and repair of the abdominal incisional hernia were performed. Cytology of ascites was negative. The postoperative pathological diagnosis was squamous cell carcinoma arising from teratoma, and the postoperative clinical diagnosis was stage IA ovarian cancer. It was assumed that the mature cystic teratoma which had been detected in the right ovary 10 years earlier had undergone malignant transformation.
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spelling doaj-art-41dc41ad107c4660befa4d69fcbb8ce82025-02-03T01:28:37ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922017-01-01201710.1155/2017/29479272947927Malignant Transformation of Mature Cystic Teratoma Diagnosed after a 10-Year IntervalMariko Jitsumori0Satoru Munakata1Toshiya Yamamoto2Department of Obstetrics and Gynecology, Sakai City Medical Center, Sakai, JapanDepartment of Pathology, Sakai City Medical Center, Sakai, JapanDepartment of Obstetrics and Gynecology, Sakai City Medical Center, Sakai, JapanA 67-year-old uniparous woman had undergone surgery for acute perforated gastric ulcer 10 years prior to the current presentation. Although abdominal computed tomography (CT) performed at that point had revealed a mature cystic teratoma measuring 6 cm in diameter in the right ovary, it was left untreated. She visited the department of surgery at our hospital with chief complaints of appetite loss, nausea, and vomiting that had persisted for the prior two weeks. She was admitted with a diagnosis of ileus attributed to an abdominal incisional hernia. CT performed on admission revealed a tumor measuring 21 cm in diameter with mural nodules in the right ovary. Thus, surgery was performed under suspicion of malignant transformation of the previously detected ovarian mature cystic teratoma. While neither lymphadenopathy nor distant metastasis was detected by imaging studies, bilateral adnexectomy and repair of the abdominal incisional hernia were performed. Cytology of ascites was negative. The postoperative pathological diagnosis was squamous cell carcinoma arising from teratoma, and the postoperative clinical diagnosis was stage IA ovarian cancer. It was assumed that the mature cystic teratoma which had been detected in the right ovary 10 years earlier had undergone malignant transformation.http://dx.doi.org/10.1155/2017/2947927
spellingShingle Mariko Jitsumori
Satoru Munakata
Toshiya Yamamoto
Malignant Transformation of Mature Cystic Teratoma Diagnosed after a 10-Year Interval
Case Reports in Obstetrics and Gynecology
title Malignant Transformation of Mature Cystic Teratoma Diagnosed after a 10-Year Interval
title_full Malignant Transformation of Mature Cystic Teratoma Diagnosed after a 10-Year Interval
title_fullStr Malignant Transformation of Mature Cystic Teratoma Diagnosed after a 10-Year Interval
title_full_unstemmed Malignant Transformation of Mature Cystic Teratoma Diagnosed after a 10-Year Interval
title_short Malignant Transformation of Mature Cystic Teratoma Diagnosed after a 10-Year Interval
title_sort malignant transformation of mature cystic teratoma diagnosed after a 10 year interval
url http://dx.doi.org/10.1155/2017/2947927
work_keys_str_mv AT marikojitsumori malignanttransformationofmaturecysticteratomadiagnosedaftera10yearinterval
AT satorumunakata malignanttransformationofmaturecysticteratomadiagnosedaftera10yearinterval
AT toshiyayamamoto malignanttransformationofmaturecysticteratomadiagnosedaftera10yearinterval