A Rare Malignant Peripheral Nerve Sheath Tumor of the Maxilla Mimicking a Periapical Lesion
Malignant peripheral nerve sheath tumor is a malignant neoplasm that is rarely found in the oral cavity. About 50% of this tumor occurs in patients with neurofibromatosis type I and comprises approximately 10% of all soft tissue sarcomas of head and neck region. Intraosseous malignant peripheral ner...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2016/4101423 |
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| author | José Alcides Arruda Pamella Álvares Luciano Silva Alexandrino Pereira dos Santos Neto Cleomar Donizeth Rodrigues Antônio Caubi Marcia Silveira Sandra Sayão Ana Paula Sobral |
| author_facet | José Alcides Arruda Pamella Álvares Luciano Silva Alexandrino Pereira dos Santos Neto Cleomar Donizeth Rodrigues Antônio Caubi Marcia Silveira Sandra Sayão Ana Paula Sobral |
| author_sort | José Alcides Arruda |
| collection | DOAJ |
| description | Malignant peripheral nerve sheath tumor is a malignant neoplasm that is rarely found in the oral cavity. About 50% of this tumor occurs in patients with neurofibromatosis type I and comprises approximately 10% of all soft tissue sarcomas of head and neck region. Intraosseous malignant peripheral nerve sheath tumor of the maxilla is rare. This article is the first to address malignant peripheral nerve sheath tumor of the maxilla presenting as a periapical radiolucency on nonvital endodontically treated teeth in the English medical literature. Surgical approaches to malignant soft tissue tumor vary based on the extent of the disease, age of the patient, and pathological findings. A rare case of intraosseous malignant peripheral nerve sheath tumor is reported in a 16-year-old woman. The patient presented clinically with a pain involving the upper left incisors region and with defined unilocular periapical radiolucency lesion involved between the upper left incisors. An incisional biopsy was made. Histological and immunohistochemical examination were positive for S-100 protein and glial fibrillary acidic protein showed that the lesion was an intraosseous malignant peripheral nerve sheath tumor of the maxilla. Nine years after the surgery, no regional recurrence was observed. |
| format | Article |
| id | doaj-art-41d1b444f2644c07ba3edbfdff3c838c |
| institution | Kabale University |
| issn | 2090-6447 2090-6455 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dentistry |
| spelling | doaj-art-41d1b444f2644c07ba3edbfdff3c838c2025-02-03T05:48:17ZengWileyCase Reports in Dentistry2090-64472090-64552016-01-01201610.1155/2016/41014234101423A Rare Malignant Peripheral Nerve Sheath Tumor of the Maxilla Mimicking a Periapical LesionJosé Alcides Arruda0Pamella Álvares1Luciano Silva2Alexandrino Pereira dos Santos Neto3Cleomar Donizeth Rodrigues4Antônio Caubi5Marcia Silveira6Sandra Sayão7Ana Paula Sobral8Faculdade de Odontologia de Pernambuco, Universidade de Pernambuco, Avenida General Newton Cavalcante, 1650 Aldeia dos Camarás, 54.753-020 Camaragibe, PE, BrazilFaculdade de Odontologia de Pernambuco, Universidade de Pernambuco, Avenida General Newton Cavalcante, 1650 Aldeia dos Camarás, 54.753-020 Camaragibe, PE, BrazilFaculdade de Odontologia de Pernambuco, Universidade de Pernambuco, Avenida General Newton Cavalcante, 1650 Aldeia dos Camarás, 54.753-020 Camaragibe, PE, BrazilFaculdade de Odontologia de Pernambuco, Universidade de Pernambuco, Avenida General Newton Cavalcante, 1650 Aldeia dos Camarás, 54.753-020 Camaragibe, PE, BrazilFaculdades Integradas da União Educacional do Planalto Central, SIGA Área Especial para Indústria, no 2, Setor Leste, 72.445-020, Gama, DG, BrazilFaculdade de Odontologia de Pernambuco, Universidade de Pernambuco, Avenida General Newton Cavalcante, 1650 Aldeia dos Camarás, 54.753-020 Camaragibe, PE, BrazilFaculdade de Odontologia de Pernambuco, Universidade de Pernambuco, Avenida General Newton Cavalcante, 1650 Aldeia dos Camarás, 54.753-020 Camaragibe, PE, BrazilFaculdade de Odontologia de Pernambuco, Universidade de Pernambuco, Avenida General Newton Cavalcante, 1650 Aldeia dos Camarás, 54.753-020 Camaragibe, PE, BrazilFaculdade de Odontologia de Pernambuco, Universidade de Pernambuco, Avenida General Newton Cavalcante, 1650 Aldeia dos Camarás, 54.753-020 Camaragibe, PE, BrazilMalignant peripheral nerve sheath tumor is a malignant neoplasm that is rarely found in the oral cavity. About 50% of this tumor occurs in patients with neurofibromatosis type I and comprises approximately 10% of all soft tissue sarcomas of head and neck region. Intraosseous malignant peripheral nerve sheath tumor of the maxilla is rare. This article is the first to address malignant peripheral nerve sheath tumor of the maxilla presenting as a periapical radiolucency on nonvital endodontically treated teeth in the English medical literature. Surgical approaches to malignant soft tissue tumor vary based on the extent of the disease, age of the patient, and pathological findings. A rare case of intraosseous malignant peripheral nerve sheath tumor is reported in a 16-year-old woman. The patient presented clinically with a pain involving the upper left incisors region and with defined unilocular periapical radiolucency lesion involved between the upper left incisors. An incisional biopsy was made. Histological and immunohistochemical examination were positive for S-100 protein and glial fibrillary acidic protein showed that the lesion was an intraosseous malignant peripheral nerve sheath tumor of the maxilla. Nine years after the surgery, no regional recurrence was observed.http://dx.doi.org/10.1155/2016/4101423 |
| spellingShingle | José Alcides Arruda Pamella Álvares Luciano Silva Alexandrino Pereira dos Santos Neto Cleomar Donizeth Rodrigues Antônio Caubi Marcia Silveira Sandra Sayão Ana Paula Sobral A Rare Malignant Peripheral Nerve Sheath Tumor of the Maxilla Mimicking a Periapical Lesion Case Reports in Dentistry |
| title | A Rare Malignant Peripheral Nerve Sheath Tumor of the Maxilla Mimicking a Periapical Lesion |
| title_full | A Rare Malignant Peripheral Nerve Sheath Tumor of the Maxilla Mimicking a Periapical Lesion |
| title_fullStr | A Rare Malignant Peripheral Nerve Sheath Tumor of the Maxilla Mimicking a Periapical Lesion |
| title_full_unstemmed | A Rare Malignant Peripheral Nerve Sheath Tumor of the Maxilla Mimicking a Periapical Lesion |
| title_short | A Rare Malignant Peripheral Nerve Sheath Tumor of the Maxilla Mimicking a Periapical Lesion |
| title_sort | rare malignant peripheral nerve sheath tumor of the maxilla mimicking a periapical lesion |
| url | http://dx.doi.org/10.1155/2016/4101423 |
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