Cardiovascular Complications During Delivery Hospitalization in Patients With Psoriasis
Background: Psoriasis in pregnancy is associated with adverse maternal outcomes. However, there are limited data on this subject. Objectives: The purpose of our study was to investigate the association between psoriasis and related cardiovascular complications during delivery. Methods: The National...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-02-01
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| Series: | JACC: Advances |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772963X24008433 |
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| author | Ankit Agrawal, MD Sharmeen Sorathia, MD Umesh Bhagat, MD Salman Zahid, MD Aro Daniela Arockiam, MD Aqieda Bayat, MD Ahmad Safdar, MD Akiva Rosenzveig, MD Muhammad Majid, MD Sanya Chandna, MD Rahul Gupta, MD Brittany Weber, MD, PhD Erin D. Michos, MD, MHS |
| author_facet | Ankit Agrawal, MD Sharmeen Sorathia, MD Umesh Bhagat, MD Salman Zahid, MD Aro Daniela Arockiam, MD Aqieda Bayat, MD Ahmad Safdar, MD Akiva Rosenzveig, MD Muhammad Majid, MD Sanya Chandna, MD Rahul Gupta, MD Brittany Weber, MD, PhD Erin D. Michos, MD, MHS |
| author_sort | Ankit Agrawal, MD |
| collection | DOAJ |
| description | Background: Psoriasis in pregnancy is associated with adverse maternal outcomes. However, there are limited data on this subject. Objectives: The purpose of our study was to investigate the association between psoriasis and related cardiovascular complications during delivery. Methods: The National Inpatient Sample was used to identify hospitalizations for delivery from 2011 to 2020. Propensity score matching was performed to study the association of psoriasis with the primary outcomes of in-hospital medical and obstetric complications. Results: A total of 37,482,206 weighted delivery hospitalizations in women ≥18 years were identified; of which, 23,588 patients had psoriasis. Pregnant patients with psoriasis had a higher incidence of complications during delivery, including preeclampsia/eclampsia, acute kidney injury, pulmonary edema, cardiac arrhythmias, and venous thromboembolism compared to those without psoriasis. In propensity-matched analysis, psoriasis was significantly associated with a higher risk of preeclampsia/eclampsia (OR: 1.25, 95% CI: 1.08 to 1.43, P = 0.002) and cardiac arrhythmias (OR: 1.44, 95% CI: 1.08-1.93, P = 0.012), compared to patients without psoriasis. Conclusions: Delivery hospitalizations in patients with psoriasis are associated with a higher risk of preeclampsia/eclampsia and cardiac arrhythmias. |
| format | Article |
| id | doaj-art-41bb0963a97c4584bf2969d8d88dfbaf |
| institution | Kabale University |
| issn | 2772-963X |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | JACC: Advances |
| spelling | doaj-art-41bb0963a97c4584bf2969d8d88dfbaf2025-01-21T04:13:25ZengElsevierJACC: Advances2772-963X2025-02-0142101562Cardiovascular Complications During Delivery Hospitalization in Patients With PsoriasisAnkit Agrawal, MD0Sharmeen Sorathia, MD1Umesh Bhagat, MD2Salman Zahid, MD3Aro Daniela Arockiam, MD4Aqieda Bayat, MD5Ahmad Safdar, MD6Akiva Rosenzveig, MD7Muhammad Majid, MD8Sanya Chandna, MD9Rahul Gupta, MD10Brittany Weber, MD, PhD11Erin D. Michos, MD, MHS12Department of Cardiovascular Medicine, Heart, Vascular, and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USADepartment of Cardiovascular Medicine, Heart, Vascular, and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USADepartment of Cardiovascular Medicine, Heart, Vascular, and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USAKnight Cardiovascular Institute, Oregon Health and Science University, Portland, Oregon, USADepartment of Cardiovascular Medicine, Heart, Vascular, and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USADepartment of Cardiovascular Medicine, Heart, Vascular, and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USADepartment of Cardiovascular Medicine, Heart, Vascular, and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USADepartment of Cardiovascular Medicine, Heart, Vascular, and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USADepartment of Cardiovascular Medicine, Heart, Vascular, and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USADepartment of Cardiovascular Medicine, Heart, Vascular, and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USADepartment of Cardiovascular Medicine, Yale New Haven Hospital, New Haven, Connecticut, USADivision of Cardiovascular Imaging, Department of Cardiovascular Medicine, Heart and Vascular Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USADivision of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Address for correspondence: Dr Erin D. Michos, Division of Cardiology, Johns Hopkins Hospital, 600 N Wolfe Street, Blalock 524-B, Baltimore, Maryland 21298, USA.Background: Psoriasis in pregnancy is associated with adverse maternal outcomes. However, there are limited data on this subject. Objectives: The purpose of our study was to investigate the association between psoriasis and related cardiovascular complications during delivery. Methods: The National Inpatient Sample was used to identify hospitalizations for delivery from 2011 to 2020. Propensity score matching was performed to study the association of psoriasis with the primary outcomes of in-hospital medical and obstetric complications. Results: A total of 37,482,206 weighted delivery hospitalizations in women ≥18 years were identified; of which, 23,588 patients had psoriasis. Pregnant patients with psoriasis had a higher incidence of complications during delivery, including preeclampsia/eclampsia, acute kidney injury, pulmonary edema, cardiac arrhythmias, and venous thromboembolism compared to those without psoriasis. In propensity-matched analysis, psoriasis was significantly associated with a higher risk of preeclampsia/eclampsia (OR: 1.25, 95% CI: 1.08 to 1.43, P = 0.002) and cardiac arrhythmias (OR: 1.44, 95% CI: 1.08-1.93, P = 0.012), compared to patients without psoriasis. Conclusions: Delivery hospitalizations in patients with psoriasis are associated with a higher risk of preeclampsia/eclampsia and cardiac arrhythmias.http://www.sciencedirect.com/science/article/pii/S2772963X24008433complicationsdeliverypregnancypsoriasis |
| spellingShingle | Ankit Agrawal, MD Sharmeen Sorathia, MD Umesh Bhagat, MD Salman Zahid, MD Aro Daniela Arockiam, MD Aqieda Bayat, MD Ahmad Safdar, MD Akiva Rosenzveig, MD Muhammad Majid, MD Sanya Chandna, MD Rahul Gupta, MD Brittany Weber, MD, PhD Erin D. Michos, MD, MHS Cardiovascular Complications During Delivery Hospitalization in Patients With Psoriasis JACC: Advances complications delivery pregnancy psoriasis |
| title | Cardiovascular Complications During Delivery Hospitalization in Patients With Psoriasis |
| title_full | Cardiovascular Complications During Delivery Hospitalization in Patients With Psoriasis |
| title_fullStr | Cardiovascular Complications During Delivery Hospitalization in Patients With Psoriasis |
| title_full_unstemmed | Cardiovascular Complications During Delivery Hospitalization in Patients With Psoriasis |
| title_short | Cardiovascular Complications During Delivery Hospitalization in Patients With Psoriasis |
| title_sort | cardiovascular complications during delivery hospitalization in patients with psoriasis |
| topic | complications delivery pregnancy psoriasis |
| url | http://www.sciencedirect.com/science/article/pii/S2772963X24008433 |
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