Youthful Stem Cell Microenvironments: Rejuvenating Aged Bone Repair Through Mitochondrial Homeostasis Remodeling

Abstract Extracellular matrix (ECM) derived from mesenchymal stem cells regulates antioxidant properties and bone metabolism by providing a favorable extracellular microenvironment. However, its functional role and molecular mechanism in mitochondrial function regulation and aged bone regeneration r...

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Bibliographic Details
Main Authors: Xinfeng Zhou, Xin Tian, Jianan Chen, Yantong Li, Nanning Lv, Hao Liu, Tao Liu, Huilin Yang, Xi Chen, Yong Xu, Fan He
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202409644
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