Up-regulation of m6A writer METTL14 inhibits tumorigenesis by suppressing glycolysis in colorectal cancer

Abstract Background Colorectal cancer (CRC) is a common malignant tumor. N6-Methyladenosine (m6A) modification plays an important role in the regulation of glycolysis in tumor cells and may be a potential target for tumor therapy. Methods The role of METTL14, an m6A writer, in CRC was investigated t...

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Bibliographic Details
Main Authors: Lulu Li, Rong Zhang, Yongsheng Li
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Cancer
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Online Access:https://doi.org/10.1186/s12885-025-13532-2
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