An Experimental Dynamic Investigation of the Influence of Melatonin, Serotonin and Tryptophan on the Stability of the DNA Structure

An Experimental Dynamic Investigation of the Influence of Melatonin, Serotonin and Tryptophan on the Stability of the DNA Structure

Background: Small molecules play a crucial role in the exploration of physiological pathways and in drug development by targeting deoxyribonucleic acid (DNA). DNA is a central focus for both endogenous and exogenous ligands, which interact directly or indirectly to regulate transcription and replica...

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Bibliographic Details
Main Authors: Cristina Manuela Drăgoi, Anca Zanfirescu, Ion-Bogdan Dumitrescu, Anca Ungurianu, Denisa Marilena Margină, Alina-Crenguţa Nicolae
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Chemistry
Subjects:
ct-DNA
indole moiety
melatonin
serotonin
tryptophan
docking
Online Access:https://www.mdpi.com/2624-8549/6/5/54
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