Influence of Overweight and Obesity on Morbidity and Mortality among Hospitalized Patients in Sri Lanka: A Single-Center Analysis
Background. Current evidence regarding the association between overweight and obesity and in-hospital morbidity and mortality is inconsistent and South Asian populations are underrepresented. Methods. Data relevant to anthropometry, hospital outcomes, complications, and medical diagnoses of all acut...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-01-01
|
| Series: | Journal of Obesity |
| Online Access: | http://dx.doi.org/10.1155/2022/9172365 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832559410024546304 |
|---|---|
| author | M. D. S. A. Dilrukshi V. Thotamuna D. J. Senarath Yapa L. De Silva P. Ranasinghe P. Katulanda |
| author_facet | M. D. S. A. Dilrukshi V. Thotamuna D. J. Senarath Yapa L. De Silva P. Ranasinghe P. Katulanda |
| author_sort | M. D. S. A. Dilrukshi |
| collection | DOAJ |
| description | Background. Current evidence regarding the association between overweight and obesity and in-hospital morbidity and mortality is inconsistent and South Asian populations are underrepresented. Methods. Data relevant to anthropometry, hospital outcomes, complications, and medical diagnoses of all acute medical admissions to the National Hospital of Sri Lanka were collected over a period of 3 months. Analysis was performed with WHO international (ICs) and Asian obesity cut-offs (ACs). Results. Sample size was 2,128 (median age: 57 years [IQR: 42, 67], males: 49.7%). High prevalence of overweight (23.5%), generalized obesity (10.4%), central obesity (28.5%), and underweight (15.4%) was observed (ICs). Patients with either generalized or central obesity had significantly higher in-hospital mortality (4.8% versus 2.5%, p=0.031) and acute kidney injury (AKI) (3.9% versus 1.2%) (p=0.001) compared to normal weight. With ACs, overweight and obesity prevalence increased, without any significant increment in morbidity and mortality, but median length of hospital stay was significantly reduced in patients with generalized obesity compared to normal (3 [IQR: 2, 5] versus 4 [IQR: 2, 6], p=0.014). Infections (44.4%) and cardiovascular diseases (CVDs) (25.9%) were the most common causes of admission. Overweight and generalized obesity or central obesity were associated with increased prevalence of acute CVDs and CVD risk factors and lower prevalence of acute infections, whilst underweight showed an inverse association. Conclusion. A double burden of malnutrition and diseases were noted among hospital admissions, with obesity being a risk factor for in-hospital all-cause mortality and AKI. Overweight and obesity were associated with increased CVDs and reduced infections. Larger prospective studies are required to characterize these associations among South Asians. |
| format | Article |
| id | doaj-art-413466c9d0e14818a73e4cebb20e6ff4 |
| institution | Kabale University |
| issn | 2090-0716 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Obesity |
| spelling | doaj-art-413466c9d0e14818a73e4cebb20e6ff42025-02-03T01:30:02ZengWileyJournal of Obesity2090-07162022-01-01202210.1155/2022/9172365Influence of Overweight and Obesity on Morbidity and Mortality among Hospitalized Patients in Sri Lanka: A Single-Center AnalysisM. D. S. A. Dilrukshi0V. Thotamuna1D. J. Senarath Yapa2L. De Silva3P. Ranasinghe4P. Katulanda5National Hospital of Sri LankaDiabetes Trial UnitDiabetes Trial UnitDiabetes Trial UnitNational Hospital of Sri LankaNational Hospital of Sri LankaBackground. Current evidence regarding the association between overweight and obesity and in-hospital morbidity and mortality is inconsistent and South Asian populations are underrepresented. Methods. Data relevant to anthropometry, hospital outcomes, complications, and medical diagnoses of all acute medical admissions to the National Hospital of Sri Lanka were collected over a period of 3 months. Analysis was performed with WHO international (ICs) and Asian obesity cut-offs (ACs). Results. Sample size was 2,128 (median age: 57 years [IQR: 42, 67], males: 49.7%). High prevalence of overweight (23.5%), generalized obesity (10.4%), central obesity (28.5%), and underweight (15.4%) was observed (ICs). Patients with either generalized or central obesity had significantly higher in-hospital mortality (4.8% versus 2.5%, p=0.031) and acute kidney injury (AKI) (3.9% versus 1.2%) (p=0.001) compared to normal weight. With ACs, overweight and obesity prevalence increased, without any significant increment in morbidity and mortality, but median length of hospital stay was significantly reduced in patients with generalized obesity compared to normal (3 [IQR: 2, 5] versus 4 [IQR: 2, 6], p=0.014). Infections (44.4%) and cardiovascular diseases (CVDs) (25.9%) were the most common causes of admission. Overweight and generalized obesity or central obesity were associated with increased prevalence of acute CVDs and CVD risk factors and lower prevalence of acute infections, whilst underweight showed an inverse association. Conclusion. A double burden of malnutrition and diseases were noted among hospital admissions, with obesity being a risk factor for in-hospital all-cause mortality and AKI. Overweight and obesity were associated with increased CVDs and reduced infections. Larger prospective studies are required to characterize these associations among South Asians.http://dx.doi.org/10.1155/2022/9172365 |
| spellingShingle | M. D. S. A. Dilrukshi V. Thotamuna D. J. Senarath Yapa L. De Silva P. Ranasinghe P. Katulanda Influence of Overweight and Obesity on Morbidity and Mortality among Hospitalized Patients in Sri Lanka: A Single-Center Analysis Journal of Obesity |
| title | Influence of Overweight and Obesity on Morbidity and Mortality among Hospitalized Patients in Sri Lanka: A Single-Center Analysis |
| title_full | Influence of Overweight and Obesity on Morbidity and Mortality among Hospitalized Patients in Sri Lanka: A Single-Center Analysis |
| title_fullStr | Influence of Overweight and Obesity on Morbidity and Mortality among Hospitalized Patients in Sri Lanka: A Single-Center Analysis |
| title_full_unstemmed | Influence of Overweight and Obesity on Morbidity and Mortality among Hospitalized Patients in Sri Lanka: A Single-Center Analysis |
| title_short | Influence of Overweight and Obesity on Morbidity and Mortality among Hospitalized Patients in Sri Lanka: A Single-Center Analysis |
| title_sort | influence of overweight and obesity on morbidity and mortality among hospitalized patients in sri lanka a single center analysis |
| url | http://dx.doi.org/10.1155/2022/9172365 |
| work_keys_str_mv | AT mdsadilrukshi influenceofoverweightandobesityonmorbidityandmortalityamonghospitalizedpatientsinsrilankaasinglecenteranalysis AT vthotamuna influenceofoverweightandobesityonmorbidityandmortalityamonghospitalizedpatientsinsrilankaasinglecenteranalysis AT djsenarathyapa influenceofoverweightandobesityonmorbidityandmortalityamonghospitalizedpatientsinsrilankaasinglecenteranalysis AT ldesilva influenceofoverweightandobesityonmorbidityandmortalityamonghospitalizedpatientsinsrilankaasinglecenteranalysis AT pranasinghe influenceofoverweightandobesityonmorbidityandmortalityamonghospitalizedpatientsinsrilankaasinglecenteranalysis AT pkatulanda influenceofoverweightandobesityonmorbidityandmortalityamonghospitalizedpatientsinsrilankaasinglecenteranalysis |