Phenotypic diversity of CTCs and tdEVs in liquid biopsies of tumour-draining veins is linked to poor prognosis in colorectal cancer

Phenotypic diversity of CTCs and tdEVs in liquid biopsies of tumour-draining veins is linked to poor prognosis in colorectal cancer

Abstract Background Circulating tumour cells (CTCs) and tumour-derived extracellular vesicles (tdEVs) have great potential for monitoring therapy response and early detection of tumour relapse, facilitating personalized adjuvant therapeutic strategies. However, their low abundance in peripheral bloo...

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Main Authors: Stefan A. Cieslik, Andrés G. Zafra, Christiane Driemel, Monica Sudarsanam, Jan-Philipp Cieslik, Georg Flügen, Levent Dizdar, Andreas Krieg, Sascha Vaghiri, Hany Ashmawy, Stephen Fung, Miriam Wilms, Leon W. M. M. Terstappen, Afroditi Nanou, Hans Neubauer, Nuh N. Rahbari, Wolfram T. Knoefel, Nikolas H. Stoecklein, Rui P. L. Neves
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Circulating tumour cells
CTCs
Tumour-derived extracellular vesicles
tdEVs
Colorectal cancer
CRC
Online Access:https://doi.org/10.1186/s13046-024-03259-6
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https://doi.org/10.1186/s13046-024-03259-6

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