Integrating in vitro and in silico approaches for exploring antidiabetic potential of dimethyl and thiomethyl indolinone derivatives.

Diabetes mellitus (DM) is a metabolic disorder caused by insulin deficiency. It is a rapidly growing problem with immense social, economic and health related problems. The market available drugs for the management of DM possess several limitations and therefore the discovery of more effective agents...

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Bibliographic Details
Main Authors: Kashif Ali, Ahmed A Elhenawy, Waqas Alam, Khalaf F Alsharif, Khalid J Alzahrani, Haroon Khan, Long Chiau Ming, Rahul G Ingle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0319987
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